Several Dosage Forms Containing Vitamin B and Their Use in Therapy

Abstract

Vitamin B plays a critical role in the synthesis of DNA and maintaining the normal functioning of tissues. Therefore, its deficiency may lead to mental problems such as depression, schizophrenia, dementia, and systemic problems such as megaloblastic anemia and peripheral neuropathy. Vitamin B deficiency may be based on nutrition, as well as the use of some drugs such as metformin and omeprazole suppress the absorption of B vitamins, which may lead to deficiency. Since B vitamin is water soluble, it cannot be stored in the body. For this reason, it should be taken continuously with food. However, in cases where the vitamin B taken with food is not sufficient for the body, it should be reinforced with drugs or dietary supplements from outside. Studies have shown that the absorption of Vitamin B is 50% higher in food supplements than in foods. It can also be used as a targeting agent in tumor therapy, due to its overexpression in some tumor cells. Due to these properties of Vitamin B, various dosage forms are being developed. In this chapter, vitamin B-containing dosage forms, their production techniques, and their use in therapy will be mentioned.

Possible prospects for the combined administration of antidepressants and antioxidants in neurological patients

“…Они широко используются в неврологической практике, в т. ч. при хронических болевых синдромах [35]. Доказана связь дефицита витаминов В с биполярным расстройством, депрессией, шизофренией, аутизмом, болезнями Альцгеймера и Паркинсона [36,37]. Витамины группы В действуют как коферменты для ферментов, которые необходимы для функционирования клеток.…”