The goal of this paper is to study fractional calculus of distributions, the generalized Abel's integral equations, as well as fractional differential equations in the distributional space D (R + ) based on inverse convolutional operators and Babenko's approach. Furthermore, we provide interesting applications of Abel's integral equations in viscoelastic systems, as well as solving other integral equations, such as π/2 θ y(ϕ) cos β ϕ(cos θ−cos ϕ) α dϕ = f (θ) , and ∞ 0 x 1/2 g(x)y(x + t)dx = f (t).