“…6 While the autoantibody may persist for up to 4 months, if haemolysis does occur, it is self-limited and rarely persists for more than 3 weeks. 6 Despite the classic association between M. pneumoniae infection and CAS, this case highlights the reality that many healthcare providers are unaware of the potential for clinically significant haemolysis in these patients. The aetiology of anaemia in our patient was presumed to be secondary to GI blood loss given his history of recurrent GI bleeds and use of anti-platelet therapy, despite a characteristic clinical scenario with peripheral blood smear morphology and laboratory results consistent with CAS secondary to infection.…”