Severe acute arsine poisoning treated by plasma exchange

Song, Yuguo; Wang, Dixin; Li, Huiling; Hao, Feng-tong; Ma, Jing; Xia, Yujing

doi:10.1080/15563650701502675

Cited by 16 publications

(10 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A recent case report has suggested plasma exchange as an effective early treatment intervention for acute arsenic poisoning [19]. In our case, plasmapheresis was performed regarding the hypothesis of a haemolytic-uremic syndrome, before any toxicodrome was suspected.…”

Section: Discussionmentioning

confidence: 97%

Haemolytic anaemia secondary to arsenic poisoning: a case report

Correia

Carvalho

Friões

et al. 2009

Cases J

View full text Add to dashboard Cite

We report the case of a 56-year-old white man who presented at the Emergency Department for evaluation of dark-red urine. Rapid development of acute renal failure and haemolytic anaemia initially elicited the hypothesis of a haemolytic-uremic syndrome. A previous exposure to a gas mixture containing arsenic and copper was later recognized as the probable aetiology while other differential diagnoses were excluded. Chelating treatment was promptly initiated before laboratorial confirmation of arsenic and copper poisoning. Renal and haematological recovery was gradually observed and the patient survived with no sequelae.

show abstract

Section: Discussionmentioning

confidence: 97%

Haemolytic anaemia secondary to arsenic poisoning: a case report

Correia

Carvalho

Friões

et al. 2009

Cases J

View full text Add to dashboard Cite

show abstract

“…Most patients report little or no discomfort at the time of exposure. Although a garliclike odor may be noted with higher ambient arsine concentrations, serious toxicity may result from clinically nondetectable exposures (Levvy, 1947;Apostoli et al, 1997;Thomas and Young, 2001;Young et al, 2003;Lenza, 2006;Song et al, 2006). Symptoms after sub-lethal arsine exposure may include abdominal pain, hematuria, and jaundice ( Figure 15.2).…”

Section: Acute Arsine Poisoningmentioning

confidence: 94%

“…Physical signs and their severity depend on the concentration of arsine gas and the duration of the exposure and have been mentioned in Figure 15.2 (Levvy, 1947;Apostoli et al, 1997;Thomas and Young, 2001;Young et al, 2003;Lenza, 2006;Song et al, 2006).…”

Section: Physical Signsmentioning

confidence: 97%

Arsenicals

Flora¹

2015

Handbook of Toxicology of Chemical Warfare Agents

View full text Add to dashboard Cite

“…Poisons removed via apheresis optimally have very low volumes of distribution, as a lower volume of blood is processed during a single apheresis treatment than during a standard HD treatment. Exchange transfusion and therapeutic plasma exchange have been utilized for rare poisonings not otherwise amenable extracorporeal removal, such as snake envenomation, iatrogenic poisoning with monoclonal antibodies, arsine gas, and Amanita phalloides (a highly poisonous basidiomycete mushroom) poisoning, but it is unclear how much benefit is gained via these procedures (15,25,26).…”

Section: Modalities Of Extracorporeal Therapy For Poisoningmentioning

confidence: 99%

Extracorporeal Removal of Poisons and Toxins

King

Kern

Jaar

2019

CJASN

View full text Add to dashboard Cite

Extracorporeal therapies have been used to remove toxins from the body for over 50 years and have a greater role than ever before in the treatment of poisonings. Improvements in technology have resulted in increased efficacy of removing drugs and other toxins with hemodialysis, and newer extracorporeal therapy modalities have expanded the role of extracorporeal supportive care of poisoned patients. However, despite these changes, for at least the past three decades the most frequently dialyzed poisons remain salicylates, toxic alcohols, and lithium; in addition, the extracorporeal treatment of choice for therapeutic removal of nearly all poisonings remains intermittent hemodialysis. For the clinician, consideration of extracorporeal therapy in the treatment of a poisoning depends upon the characteristics of toxins amenable to extracorporeal removal (e.g., molecular mass, volume of distribution, protein binding), choice of extracorporeal treatment modality for a given poisoning, and when the benefit of the procedure justifies additive risk. Given the relative rarity of poisonings treated with extracorporeal therapies, the level of evidence for extracorporeal treatment of poisoning is not robust; however, extracorporeal treatment of a number of individual toxins have been systematically reviewed within the current decade by the Extracorporeal Treatment in Poisoning workgroup, which has published treatment recommendations with an improved evidence base. Some of these recommendations are discussed, as well as management of a small number of relevant poisonings where extracorporeal therapy use may be considered.

show abstract

Severe acute arsine poisoning treated by plasma exchange

Cited by 16 publications

References 28 publications

Haemolytic anaemia secondary to arsenic poisoning: a case report

Haemolytic anaemia secondary to arsenic poisoning: a case report

Arsenicals

Extracorporeal Removal of Poisons and Toxins

Contact Info

Product

Resources

About