Severe Acute Endogenous Endophthalmitis with Staphylococcus Epidermidis in a Systemically Well Patient

Whist, Eline; Hollenbach, Eugene; Dunlop, Anthony

doi:10.4137/oed.s5883

Cited by 5 publications

(3 citation statements)

References 10 publications

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“…A similar case report was reported by Whist E et al, where in a systemically normal with no locus of infection went on develop Staphylococcus epidermidis EE [11]. Unfortunately, as this case shows, EBE can occasionally mimic severe panuveitis, in which case salvaging vision or eye could be extremely difficult.…”

Section: Induced Endogenous Endophthalmitis Abstractmentioning

confidence: 79%

Methicillin Resistant Staphylococcus Epidermidis Induced Endogenous Endophthalmitis

Vivekanand¹

2014

JCDR

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Section: Induced Endogenous Endophthalmitis Abstractmentioning

confidence: 79%

Methicillin Resistant Staphylococcus Epidermidis Induced Endogenous Endophthalmitis

Vivekanand¹

2014

JCDR

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“…The patient was treated with intravitreal foscarnet + vancomycin + amikacin, intravenous vancomycin, PPV and lensectomy. The patient regained vision of HM [ 41 ] ( Table 1 , 2 ).…”

Section: Resultsmentioning

confidence: 99%

Metastatic endophthalmitis - Has the trend of causative organism changed in the modern antibiotic era - A Systematic Review

Wadhwani¹,

Mishra²,

Manika³

et al. 2020

rjo

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Endogenous endophthalmitis, EE, a less common form of endophthalmitis, occurs when the microorganisms spread to the eye through the bloodstream, from a septic focus elsewhere in the body, that breaches into the integrity of the eyeball itself. The etiopathogenesis of endogenous endophthalmitis has changed over the past two decades, the aim of this review being to study the changing trends in causative organism in the era of modern antibiotics.

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“…8 Gram negative organisms like E. coli, N. meningitidis and Klebsiella have been reported to cause endogenous endophthalmitis 9,10 Though the endophthalmitis occurs more commonly in immunocompromised patients, many studies have shown its occurrence in systemically well patients. Gupta et al 4 12 in 2011 reported severe endogenous endophthalmitis caused by Staphahylococcus epidermidis in a systemically well individual. In addition to routine laboratory tests testing for HIV infection should be done in otherwise healthy persons with endogenous endophthalmitis.…”

Section: Discussionmentioning

confidence: 99%

Contaminated Dextrose Normal Saline: A Cause of Endogenous Endophthalmitis in an Immunocompetent Subject

Chaudhry¹

2012

Delhi Journal of Ophthalmology

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Endogenous endophthalmitis is an intraocular infection caused by haematogenous spread of microorganisms from distant foci. It accounts for 2-8% of all cases of endophthalmitis. The common causative organisms include Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas andEndogenous Endophthalmitis is relatively rare but sight threatening intraocular infection caused by haematogenous spread of micro organisms from a distant focus of infection elsewhere in the body. It accounts for 2-8% of all cases of endophthalmitis.1 It can affect patients of any age or sex. Endogenous endophthalmitis usually occurs in immunocomromised subjects although cases have been reported among immunocompetent patients. The predisposing factors include chronic metabolic diseases like diabetes mellitus, chronic renal failure, malignancy, acquired immuno deficiency syndrome (AIDS), intravenous drug abuse or after invasive procedures.2 Studies have reported that nearly 90% cases of endogenous endophthalmitis occur in patients having some or the other predisposing factor but increasingly cases have been reported in the literature among apparently healthy individuals. Dental surgery, contaminated intravenous fluids, enteric fever, gastroenteritis and intravesicular injections of M.bovis or Bacillus Calmette Guerin for bladder carcinoma have been reported as risk factors in the immunocompetent subjects. 3-5The common causative organisms include Staphylococcus aureus and Streptococcus pneumonia. Although cases of Pseudomonas and Klebsiella endophthalmitis have been reported among immunocompetent subjects. 6,7 Common fungal isolates are Candida and Aspergillus. 4 We report a case of endogenous endophthalmitis in an immunocompetent subject after intravenous fluid therapy for gastroenteritis. Case ReportA twenty eight year old female presented with rapidly progressive loss of vision in the left eye for one week associated with mild pain. She was apparently healthy with no history suggestive of any autoimmune disease, immunosuppression or chronic systemic illness. There was no history of anorexia, weight loss, nausea, headache, fever, hearing loss, skin wounds, ulcers of mouth or genitalia, ocular trauma or previous ocular surgery. History of intravenous drug abuse and other risk taking behaviour were also excluded. One week prior to onset of symptoms, the patient developed an attack of acute gastroenteritis for which she was given intravenous dextrose normal saline (DNS) by some health care professional in rural settings. She was relieved of the gastrointestinal symptoms but developed diminution of vision in the left eye two days after intravenous fluid infusion. On examination her visual acuity in right eye was 6/6 and in left eye was hand moments only. Slit lamp examination of left eye revealed mild flare and 2+ cells in anterior chamber. Fundus examination showed the presence of vitreous exudates extending to posterior pole near macula. Subretinal abscess occupying the posterior pole was also present (Figure 1a & b). Ocular exam...

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Severe Acute Endogenous Endophthalmitis with Staphylococcus Epidermidis in a Systemically Well Patient

Cited by 5 publications

References 10 publications

Methicillin Resistant Staphylococcus Epidermidis Induced Endogenous Endophthalmitis

Methicillin Resistant Staphylococcus Epidermidis Induced Endogenous Endophthalmitis

Metastatic endophthalmitis - Has the trend of causative organism changed in the modern antibiotic era - A Systematic Review

Contaminated Dextrose Normal Saline: A Cause of Endogenous Endophthalmitis in an Immunocompetent Subject

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