Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in vaccinated and unvaccinated healthcare personnel in a Veterans’ Affairs healthcare system

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in vaccinated and unvaccinated healthcare personnel in a Veterans' Affairs healthcare system.

An outbreak of SARS‐CoV‐2 on a transplant unit in the early vaccination era

“…27,28 To prevent healthcare-associated COVID-19 cases, it is vital to vaccinate hospital staff, particularly those caring for high-risk patient population who are at increased risk for severe COVID-19. 29 Despite the occurrence of this outbreak, vaccination rates of the staff on the transplant unit remained well below the hospital average. Therefore, targeting communication and campaigns to bolster vaccination compliance among staff, especially those working in a high-risk unit with immunocompromised patients, is essential, especially as two likely potential sources of our outbreak included staff-to-staff and staffto-patient transmission events.…”

“…To prevent healthcare‐associated COVID‐19 cases, it is vital to vaccinate hospital staff, particularly those caring for high‐risk patient population who are at increased risk for severe COVID‐19 29 . Despite the occurrence of this outbreak, vaccination rates of the staff on the transplant unit remained well below the hospital average.…”

Increase in the coronavirus disease 2019 (COVID-19) attack rate of fully vaccinated healthcare workers with high-risk household exposures correlates with the rise of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) B.1.617.2 (delta) variant

“…None of the vaccinated healthcare workers who acquired COVID-19 required hospitalization or developed severe disease, which is consistent with other studies conducted before and after the Delta variant became dominant. 3,4 Our data suggests that the Delta variant has impacted the attack rate following household exposure of healthcare providers compared to previous SARS-CoV-2 variants, even after HCW were fully vaccinated. Spousal relationship has previously been shown to be a high risk for secondary infection, with a mean household secondary attack rate of spouses of 37.8% in prevaccination data .…”

Boosters reduce in-hospital mortality in patients with COVID-19: An observational cohort analysis

“…Smaller studies on fully vaccinated healthcare workers who subsequently developed SARS-CoV-2 infections demonstrated rates of breakthrough infection between 0.05% and 11.6%. 8 , 9 , 10 , 11…”