Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-1) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in pregnancy – An overview

Abstract

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-1) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections, like most other viruses that affect the respiratory tract can cause severe maternal illness and adverse pregnancy outcomes. They are not only highly transmissible (acquired through droplets), but Host reservoirs such as dromedary camels for MERS-CoV and masked palm civet for SARS-CoV are critical links in the onset of outbreaks. Clinically they present with flu-like symptoms and therefore a high index of suspicion is required to ensure timely diagnosis and tailored management. Although there are not many reported series on these infections in pregnancy they seem to be associated with an increased risk of preterm delivery and maternal mortality. Diagnosis is made by PCR from nasopharyngeal swabs. There are currently no effective anti-viral agents for these viruses but following infections various agents have been administered to patients. The most important aspect of management should be early identification of deterioration and intensive support and prevention of transmission. Our understanding of the evidence of the impact of both infections on pregnancies suggests the potential for future repeat outbreaks, hence the importance of maintaining vigilance across healthcare systems.

Aceptación de la de vacunación contra la COVID-19 en mujeres peruanas embarazadas: Actitudes y factores asociados

“…No obstante, es importante mencionar que en nuestro estudio fue menor el porcentaje de las gestantes quienes no se vacunarían por esta razón. Esto es importante, pues durante el embarazo se producen varios cambios fisiológicos y hormonales que la predisponen a la infección de algunos patógenos respiratorios (Chen et al, 2020), tal y como se ha visto en pandemias previas, como el Síndrome Respiratorio Agudo Severo (SARS) y el Síndrome Respiratorio de Oriente Medio (MERS) (Babarinsa et al, 2021). Por esto es importante no solo que se priorice a este grupo de mujeres en la vacunación, sino que se realicen campañas de difusión de la información y concientización para que las gestantes se muestren más dispuestas a vacunarse.…”

Solar energy assisted thermal treatment model to decontaminate airborne viruses in hospital

“…The airborne virus spreads rapidly and intensifies the risk of diseases in the less ventilated indoor built environment [2] . Coronavirus is a single standard RNA (Ribonucleic acid) virus from the coronaviridae group, spread through airborne routes [3] . The evolution of airborne viruses shown in Fig.…”

“…The Avian influenza A virus has infected 134 people, resulting in 45 fatalities. The cases of SARS-CoV-1 were first found in Hong Kong and China in 2003 and infected thousands of people worldwide, along with 800 causalities [3] , [7] . However, the MERS-CoV was first identified in an infected patient hospitalized in Saudi Arabia in 2012.…”

“…However, the MERS-CoV was first identified in an infected patient hospitalized in Saudi Arabia in 2012. MERS-CoV is a beta-coronavirus and is from the same family as SARS-CoV-1 [3] . Mouse Hepatitis Virus (MHV), a coronavirus particular to mice, was first isolated in 1949 and found to be an exceedingly contagious disease.…”

Complete Blood Count Peculiarities in Pregnant SARS-CoV-2-Infected Patients at Term: A Cohort Study

“…Pregnancy, by virtue of its inherent physiological adaptations, would be expected to increase the risk of morbidity associated with COVID-19, particularly owing to a relatively immunocompromised state secondary to alterations within the body’s cell-mediated immune response and inflammatory mechanisms [ 3 , 4 ]. Therefore, it is imperative to closely monitor laboratory parameters, including the white blood cell count, lymphocyte count, and C-reactive protein, along with other imaging features in computed tomography chest scans, to promptly prevent, diagnose, and treat SARS-CoV-2 infection during pregnancy [ 5 , 6 ].…”