Severe Chemical Colitis Due to Hydrogen Peroxide Enema

Severe rectal burn induced by hot normal saline enema: a case report

“…Rectal burn is quite rare. In Western countries, it is mainly caused by a hot coffee or hydrogen peroxide enema in patients with constipation, which causes thermal or chemical injury to the rectal mucosa [ 1 , 2 ]. In rural China, rectal burn is mainly caused by an enema using folk remedies.…”

On The Hot Seat: A Rare Cause of Rectal Pain

“…1 Hydrogen peroxide has been used for multiple applications throughout the years, including treatment for meconium ileus, constipation, and fecal impaction. 3 Hydrogen peroxide has also been widely used as an endoscopic disinfectant, which has led to multiple reports of inadvertent iatrogenic hydrogen peroxide-induced enteritis. 2 It has also been reported that when used in large volumes, it can result in colonic gangrene and rupture, as well as fulminant colitis.…”