2012
DOI: 10.1182/blood.v120.21.366.366
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Severe Depression Following Recovery From Thrombotic Thrombocytopenic Purpura (TTP)

Abstract: 366 Introduction Recovery from an acute episode of TTP is typically assumed to be complete. However patients from the Oklahoma TTP-HUS Registry have often described persistent problems with memory, concentration, and endurance. Our previous studies have documented long-term deficits in quality-of-life and cognitive functioning. We have also observed an unexpectedly high frequency of severe depression. Therefore we documented the relative frequency of severe d… Show more

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“…Albumin/creatinine ratio (ACR), measured in 37 (80%) of the 46 surviving patients in 2011 (median follow‐up 5.9 years, range 1.1–15.7), was originally reported using a cut point of ≥ 30 μg mg −1 and was not significantly different ( P = 0.793) . However, albuminuria was reanalyzed using the more stringent cut point of ACR ≥ 10 mg g −1 because ‘high normal’ ACR of 10–29 mg g −1 predicts development of hypertension and is associated with increased mortality .…”
Section: Resultsmentioning
confidence: 99%
“…Albumin/creatinine ratio (ACR), measured in 37 (80%) of the 46 surviving patients in 2011 (median follow‐up 5.9 years, range 1.1–15.7), was originally reported using a cut point of ≥ 30 μg mg −1 and was not significantly different ( P = 0.793) . However, albuminuria was reanalyzed using the more stringent cut point of ACR ≥ 10 mg g −1 because ‘high normal’ ACR of 10–29 mg g −1 predicts development of hypertension and is associated with increased mortality .…”
Section: Resultsmentioning
confidence: 99%