Severe disseminated intravascular coagulation complicated by acute renal failure during pregnancy

Pu, Yuqun

doi:10.5847/wjem.j.1920-8642.2023.072

Cited by 1 publication

(2 citation statements)

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“…Additionally, the impaired blood flow to the kidneys caused by DIC, compounded by the hemodynamic fluctuations during surgery and the challenges of coagulopathy, can lead to acute renal failure [15]. Oliguria, a common feature of DIC-induced renal dysfunction, indicates reduced kidney filtration capacity, which may require dialysis, as was observed in this case [15].…”

Section: Discussionmentioning

confidence: 69%

“…The inflammatory cascade, initiated by placental abruption and aggravated by substance abuse, can contribute to the dysfunction of the endothelium (the inner lining of blood vessels) and the leakage of fluids into the lungs, resulting in noncardiogenic pulmonary edema [14]. Additionally, the impaired blood flow to the kidneys caused by DIC, compounded by the hemodynamic fluctuations during surgery and the challenges of coagulopathy, can lead to acute renal failure [15]. Oliguria, a common feature of DIC-induced renal dysfunction, indicates reduced kidney filtration capacity, which may require dialysis, as was observed in this case [15].…”

Section: Discussionmentioning

confidence: 99%

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Emergency Hysterectomy Following Placental Abruption in a Patient With a History of Substance Abuse: A Case Report

Ansari,

Al Sayed,

Patibandla

et al. 2024

Cureus

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Placental abruption is a serious medical condition that can occur during pregnancy, involving the premature separation of the placenta from the inner uterine wall before childbirth. This detachment often leads to severe bleeding, and if conventional methods prove ineffective in managing the bleeding, a hysterectomy may be deemed necessary to ensure the mother's safety. This case report details the management of a 22year-old female, gravida IV, para III, who experienced placental abruption during her fourth pregnancy. An emergent cesarean section resulted in severe postpartum hemorrhage and disseminated intravascular coagulation (DIC). Positive drug tests for cocaine and methamphetamines added further complexity, leading to an unplanned hysterectomy for life-saving measures. This case underscores the critical importance of early recognition, multidisciplinary collaboration, and timely intervention in managing obstetric emergencies within the context of substance abuse.

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Section: Discussionmentioning

confidence: 69%