Severe drought exposure in utero associates to children’s epigenetic age acceleration in a global climate change hot spot

Qiao, Xi; Straight, Bilinda; Ngo, Duy; Hilton, Charles E.; Owuor Olungah, Charles; Naugle, Amy; Lalancette, Claudia; Needham, Belinda L.

doi:10.1038/s41467-024-48426-7

Cited by 2 publications

(1 citation statement)

References 57 publications

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“…Droughts and floods, with their broad impact and frequent occurrence, post significant threats to the ecological environment, food security, economic development, and human health [1][2][3][4]. Under changing environments, drought and flood disasters with spatiotemporal correlation will occur continuously or interact with each other to develop into dry and wet combination events (DWCEs) [5,6], increasing the scope and intensity of the disaster and causing more serious losses to society.…”

Section: Introductionmentioning

confidence: 99%

Quantifying the Impacts of Dry–Wet Combination Events on Vegetation Vulnerability in the Loess Plateau under a Changing Environment

Dong,

Gao,

Huang

et al. 2024

Water

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Extreme drought and flood events, as well as their combined events, pose significant challenges to global sustainable socio-economic development and ecological health. However, the impact of dry–wet combination events (DWCEs) on vegetation vulnerability remains to be investigated. The Loess Plateau (LP) was selected as the study area to explore the response time of vegetation to precipitation index changes by optimal correlation coefficient; then, the impact of different DWCEs on vegetation vulnerability under moderate and severe scenarios was analyzed; finally, a vegetation loss probability model was constructed based on the copula function and Bayesian framework, to quantify the vegetation loss probability under DWCEs stress. The results indicate that: (1) normalized difference vegetation index (NDVI) shows an upward trend in spring, summer, and autumn, with the proportion of areas are 90.5%, 86.2%, and 95.4%, respectively, and show an insignificant trend in winter; (2) the response time of vegetation to precipitation index changes tends to be one or two seasons; (3) moderate scenarios have more influence than severe scenarios, dry-to-wet events (DWEs), wet-to-dry events (WDE) and continuous dry events (CDE) in spring-summer have a significant impact on summer vegetation of Ningxia and Shanxi, and WDE and CDE have a higher impact on autumn vegetation. (4) in terms of the probability of vegetation loss, DWE, and CDE cause higher losses to summer vegetation, while WDE and CDE cause higher losses to autumn vegetation. This study quantifies the impact of adjacent seasonal DWCE stress on future vegetation vulnerability.

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Section: Introductionmentioning

confidence: 99%

Quantifying the Impacts of Dry–Wet Combination Events on Vegetation Vulnerability in the Loess Plateau under a Changing Environment

Dong,

Gao,

Huang

et al. 2024

Water

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The impact of climate change-related disasters on mental health and epigenetics: a narrative review

Roe,

Khov,

Kim

et al. 2024

Front. Epigenet. Epigenom.

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Climate change has contributed to an increase in the frequency and intensity of natural disasters such as droughts, wildfires, hurricanes, and floods, leading to both immediate physical harm and long-term mental health consequences. Survivors often experience psychological distress, including anxiety, depression, and post-traumatic stress disorder (PTSD), as a result of these traumatic events. This narrative review explores the intersection of climate change-related disasters, mental health outcomes, and epigenetic modifications. Specifically, we summarize recent findings on how environmental stressors influence both mental health and epigenetic changes, such as DNA methylation. Emerging evidence suggests that epigenetic mechanisms, particularly DNA methylation, could mediate the effects of climate change-related stress on mental health, potentially contributing to the onset of mental disorders like depression, panic disorder, autism spectrum disorder, and attention deficit hyperactivity disorder. We also discuss other epigenetic mechanisms, such as histone modifications and non-coding RNAs, and emphasize the importance of longitudinal studies to capture the dynamic nature of epigenetic changes over time. Finally, we propose future research directions to deepen our understanding of the complex relationships between climate change-related disasters, mental health outcomes, and epigenetic mechanisms, which will pave the way for more effective mental health interventions and policy integration.

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Severe drought exposure in utero associates to children’s epigenetic age acceleration in a global climate change hot spot

Cited by 2 publications

References 57 publications

Quantifying the Impacts of Dry–Wet Combination Events on Vegetation Vulnerability in the Loess Plateau under a Changing Environment

Quantifying the Impacts of Dry–Wet Combination Events on Vegetation Vulnerability in the Loess Plateau under a Changing Environment

The impact of climate change-related disasters on mental health and epigenetics: a narrative review

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