Severe exacerbations and BODE index: Two independent risk factors for death in male COPD patients

Soler-Cataluña, Juan José; Martínez‐García, Miguel Ángel; Sánchez, L.; Tordera, Miguel Perpiñá; Sánchez, Pilar Román

doi:10.1016/j.rmed.2008.12.005

Cited by 273 publications

(207 citation statements)

References 26 publications

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“…Since then, other multidimensional scales have been developed. These new scales aim to improve the prognostic ability of the BODE index while simultaneously making them easier to use in daily clinical practice [2][3][4].…”

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confidence: 99%

Development of a decision tree to assess the severity and prognosis of stable COPD

Esteban¹,

Aróstegui²,

Moraza³

et al. 2011

Eur Respir J

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The aim of this study was to develop and validate a new method: a classification and regression tree (CART) based on easily accessible measures to predict mortality in patients with stable chronic obstructive pulmonary disease (COPD).This was a prospective study of two independent prospective cohorts: a derivation cohort with 611 recruited patients and a validation cohort with 348 patients, all followed for 5 yrs. CART analysis was used to predict 5-yr mortality risk using the following covariates from the derivation cohort: age, % predicted forced expiratory volume in 1 s (FEV1), dyspnoea, physical activity, general health and number of hospital admissions for COPD exacerbations in the previous 2 yrs.Age (o75 or ,75 yrs) provided the first branch of the COPD-CART. The highest mortality risk (0.74) was seen in patients .75 yrs of age with higher levels of dyspnoea and FEV1 ,50% pred. Patients with the lowest risk of 5-yr mortality (0.04) were ,55 yrs of age with FEV1 .35% pred and one or no recent hospitalisations for COPD exacerbations.A simple decision tree that uses variables commonly gathered by physicians can provide a quick assessment of the severity of the disease, as measured by the risk of 5-yr mortality.

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mentioning

confidence: 99%

Development of a decision tree to assess the severity and prognosis of stable COPD

Esteban¹,

Aróstegui²,

Moraza³

et al. 2011

Eur Respir J

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“…The level of severity is useful in the initial assessment of the patient and assesses the future risk of death and other complications [5,6], and impact refers to the current repercussion the disease has on the patient. As an example, there are patients with a different degree of dyspnoea or impairment in health-related quality of life for the same level of severity defined by either forced expiratory volume during the first second (FEV1) or even by the BODE (body mass index, airflow obstruction, dyspnoea and exercise capacity) index [7].…”

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confidence: 99%

The concept of control in COPD: a new proposal for optimising therapy

2014

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“…Preventive measures to reduce the impact of exacerbations are a priority [9], including patient education [10–13]. Factors reducing urgent health care utilization for patients affected by COPD were found to be general education, exercise, and physical therapy [10].…”

Section: Introductionmentioning

confidence: 99%

Influences of patient education on exacerbations and hospital admissions in patients with COPD – a longitudinal national register study

Henoch

Ekberg-Jansson²

2018

European Clinical Respiratory Journal

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Introduction: Chronic obstructive pulmonary disease (COPD) contributes to impaired health-related quality of life (HRQoL). Patient education and smoking cessation programs are recommended to reduce the number of exacerbations and hospitalizations, but the effects of such programs have yet to be explored in larger samples. Objective: The aim was to explore the longitudinal effects of patient education and smoking cessation programs on exacerbations and hospital admissions in patients with COPD. Design: This is a register study where data from the Swedish National Airway Register, including 20,666 patients with COPD, were used. Baseline measures of demographic, disease-related, and patient-reported variables were compared with a follow-up, 10–30 months after baseline. Descriptive statistics and changes between baseline and follow-up were calculated. Results: Comparing those not participating in education programs to those who did, HRQoL deteriorated significantly between baseline and follow-up in non-participants; there was no change in either exacerbations or hospitalizations in either group; there was a significant difference in baseline HRQoL between the two, and, when controlling for this, there was no significant change (p = 0.73). Patients who participated in smoking cessation programs were younger than the non-participants; mean 66.0 (standard deviations (SD) 7.8) vs. mean 68.1 (SD 8.8), p = 0.006. Among participants in smoking cessation programs, the proportion with continued smoking decreased significantly, from 76% to 66%, p < 0.001. Exacerbations at follow-up were predicted by FEV1% of predicted value and exacerbations at baseline. Hospital admissions at follow-up were predicted by baseline FEV1% of predicted value and exacerbations at baseline. Conclusions: To prevent exacerbations and hospital admissions, treatment and prevention must be prioritized in COPD care. Patient education and smoking cessation programs are beneficial, but there is a need to combine them with other interventions.

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Severe exacerbations and BODE index: Two independent risk factors for death in male COPD patients

Cited by 273 publications

References 26 publications

Development of a decision tree to assess the severity and prognosis of stable COPD

Development of a decision tree to assess the severity and prognosis of stable COPD

The concept of control in COPD: a new proposal for optimising therapy

Influences of patient education on exacerbations and hospital admissions in patients with COPD – a longitudinal national register study

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