Severe glomerulonephritis complicated by coagulopathy: Treatment with anticoagulant and immunosuppressive drugs

Outcome of idiopathic membranoproliferative glomerulonephritis in children

“…Many drugs have been proposed for the treatment of MPGN, including corticosteroids (2, 16,[18][19][20], various immunosuppressive agents (8,15,(20)(21)(22)(23) and anticoagulants with platelet inhibitors (22)(23)(24)(25). Most studies were uncontrolled.…”

Rapidly progressive acute post‐streptococcal glomerulonephritis in a child with IgA nephropathy

“…The prognosis of patients with APSGN is usually benign, with prompt clinical recovery and resolution of urinary and histological abnormalities within 1 year after an acute episode 7,8 . In a subset of patients with progressive clinical course or with histologic evidence of extensive crescent formation, however, aggressive treatment with pulse methylprednisolone, with or without cytotoxic drugs, should be considered 9,10 . Using immunohistochemistry of serial renal biopsy specimens, Masutani et al.…”

Anticoagulation in Renal Diseases: 20 Years on and What Is the Outcome?

“…In the original trial of Kincaid-Smith [47] of anticoagulation for chronic mesangio-capillary nephritis, deterioration of renal function was pre vented over a 2-year period. Good short-term results in children were reported by the Guy's nephrologists [48] and by Robson et al [49], Although there were a few cases in which the nephritis was arrested, ultimately further progression seems to have affected most cases in both centres. The main problem may be the long-term side-ef fects.…”