Severe hypothyroidism‐induced rhabdomyolysis: A case report

Abstract

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Acute Renal Injury Due to Rhabdomyolysis Induced by Severe Hypothyroidism: First Case Report from Somalia

“…The patient was also treated with intravenous fluids and levothyroxine treatment. 3 Similar to our report, this patient had no precipitating factors.…”

“… 2 Clinical features of rhabdomyolysis range from mild increases in creatinine kinase (CK) to medical emergencies like disseminated intravascular coagulation (DIC), acute renal failure, and cardiac arrhythmias. 3 Although hypothyroidism-related rhabdomyolysis can be encountered in clinical practice, it is a very unusual combination. 4 It has been known that hypothyroidism is associated with some degree of myalgia and muscle stiffness, but it can also be a cause of life-threatening rhabdomyolysis with end-organ damage.…”

Rhabdomyolysis Caused by Hypothyroidism: Research Progress

“…The intake of these foods in large amounts can cause or aggravate thyroid dysfunction, but most of these goiter-causing chemicals are inactivated when foods are cooked [37]. Although these patients have many predisposing factors, some case reports indicate that the occurrence of RM may not be related to obvious predisposing factors [4,38,40,41]. Therefore, an RM diagnosis cannot be based on whether a predisposing factor is identified in clinical practice.…”

“…Most patients have RM in the context of a history of hypothyroidism, but in rare cases, no history of thyroid disease is reported. If RM is the first symptom, the likely outcome is a missed diagnosis or misdiagnosis [38,41]. Salehi et al summarized 10 previously reported cases of RM caused by hypothyroidism in adults.…”

“…Patients with RM due to hypothyroidism have elevated serum CK and myoglobin levels [41]. However, no clear correlation has been identified between hypothyroidism severity and CK levels [15].…”