Severe laryngeal edema caused by Pseudoterranova species

Abstract

Rationale: Severe laryngeal edema can cause upper airway obstruction, which is fatal. Pseudoterranova , an uncommon nematode of the family Anisakidae, predominantly invades the stomach after ingestion of the nematodes in raw or undercooked marine fish. There have been a few reports of development of severe laryngeal edema caused by the nematode invading the base of the tongue. Patient concerns: A 69-year-old Japanese woman complained of stuffy and scratchy throat for 8 hours and reported eating sashimi, fresh slices of raw jacopever, 4 days before the first visit. Diagnosis: Endoscopy revealed a white-yellowish wriggling worm at the left side of the base of the tongue and severe edema of the larynx. Interventions: The worm was extracted using endoscopic forceps. The patient was hospitalized and treated with intravenous injection of an antibiotic and steroid. Outcomes: The symptoms and laryngeal edema disappeared the next day. The worm was identified as a 4th-stage larva of Pseudoterranova spp based on morphologic features. The serum Anisakis -specific IgE antibody level was high, at 38.6 UA/mL. Lessons: Clinicians should be aware of the possibility of severe laryngeal edema due to invasion by anisakid nematodes in the pharyngolaryngeal area in cases involving previous ingestion of raw or uncooked marine fish.

Genetic Structure of Juvenile Stages of Phocanema bulbosum (Nematoda, Chromadorea: Anisakidae) Parasitizing Commercial Fish, Atlantic Cod Gadus morhua, and American Plaice Hippoglossoides platessoides in the Barents Sea

“…The third-stage juvenile emerging from the egg is swallowed by benthic crustaceans and, moving along trophic chains, accumulates in fish [4,5]. Third-stage juveniles of these nematodes cause an important fish-borne zoonosis (e.g., [6][7][8][9][10][11][12][13]).…”

Gene expression and allergenic potential of Pseudoterranova bulbosa L3 from different infection sites in North Atlantic cod (Gadus morhua)

“…infections (Buchmann & Mehrdana, 2016; Rahmati et al., 2020; Shamsi & Sheorey, 2018). Medical case studies of Pseudoterranova infections show their pathogenic potential and relevance (Arcos et al., 2014; Arizono et al., 2011; Brunet et al., 2017; Cavallero et al., 2016; Llorens et al., 2018; Menghi et al., 2020; Mercado et al., 1997, 2001; Mitsuboshi et al., 2017; Murata et al., 2018; Nordholm et al., 2020; Pinel et al., 1996; Ramanan et al., 2013; Sánchez‐Alonso et al., 2020; Suzuki et al., 2021; Timi et al., 2014; Torres et al., 2007; Weitzel et al., 2015).…”

The Interaction of Food Allergy and Diabetes: Food Allergy Effects on Diabetic Mice by Intestinal Barrier Destruction and Glucagon-like Peptide 1 Reduction in Jejunum

“…Food allergies are reported to affect approximately 5% of infants and 3–4% of adults in Western countries [ 3 ]. The symptoms of food allergy vary from mild itching, diarrhea, and cough to severe life-threatening throat edema and anaphylactic shock [ 4 ]. Food allergies can cause chronic inflammation [ 5 , 6 , 7 ], and many studies have shown that inflammation can be linked to the pathogenesis of diabetes [ 8 , 9 , 10 ].…”

“…mTOR in the intestine may link energy supply with the production of GLP-1 in L cells [ 38 ]. The proposed mechanism of action of GLP-1 is believed to occur through activation of the PI3K/AKT signaling pathway and downstream of the mechanistic target of rapamycin (mTOR) kinase [ 4 , 5 , 8 ]. GLP-1 protects insulin-secreting cells against apoptosis and restrains high glucose-induced apoptosis by impeding oxidative stress through PI3K-dependent signaling pathways [ 1 , 9 ].…”