2015
DOI: 10.1186/s12879-015-0910-3
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Severe morbidity after antiretroviral (ART) initiation: active surveillance in HIV care programs, the IeDEA West Africa collaboration

Abstract: BackgroundThe causes of severe morbidity in health facilities implementing Antiretroviral Treatment (ART) programmes are poorly documented in sub-Saharan Africa. We aimed to describe severe morbidity among HIV-infected patients after ART initiation, based on data from an active surveillance system established within a network of specialized care facilities in West African cities.MethodsWithin the International epidemiological Database to Evaluate AIDS (IeDEA) - West Africa collaboration, we conducted a prospec… Show more

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“…By the end of 2013, almost 13 million people in lowand middle-income countries (LMICs) were receiving antiretroviral therapy (ART), and the African World Health Organization (WHO) region accounted for 7.5 million of treated patients [1,2]. ART has led to a major decrease in AIDS-related morbidity and mortality in LMICs [3][4][5] and, nowadays, non-AIDS events, driven by infectious morbidity events, account for the largest part of the encountered morbidity of HIVinfected individuals [6][7][8][9]. Most reports describing non-AIDS-related morbidity focus on severe events or on specific events, such as bacterial infectious events, and they usually focus either on untreated HIV-infected subjects or on patients initiating ART [6][7][8][9][10][11].…”
mentioning
confidence: 99%
“…By the end of 2013, almost 13 million people in lowand middle-income countries (LMICs) were receiving antiretroviral therapy (ART), and the African World Health Organization (WHO) region accounted for 7.5 million of treated patients [1,2]. ART has led to a major decrease in AIDS-related morbidity and mortality in LMICs [3][4][5] and, nowadays, non-AIDS events, driven by infectious morbidity events, account for the largest part of the encountered morbidity of HIVinfected individuals [6][7][8][9]. Most reports describing non-AIDS-related morbidity focus on severe events or on specific events, such as bacterial infectious events, and they usually focus either on untreated HIV-infected subjects or on patients initiating ART [6][7][8][9][10][11].…”
mentioning
confidence: 99%