Severe sensorimotor polyradiculoneuropathy after ingestion of ethylene glycol

Broadley, Simon; Ferguson, I T; Walton, Ben; Tomson, Charles

doi:10.1136/jnnp.63.2.261

Cited by 8 publications

(5 citation statements)

References 3 publications

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“…3). In the literature, 5th, 7th and 9th cranial nerve involvement findings after methanol poisoning have been diagnosed (9). In our case, dysarthria, dysphagia, and loss of taste sensation (cranial 7th and 9th nerve involvement) were detected in accordance with cranial nerve involvement.…”

Section: Discussionsupporting

confidence: 56%

Brain imaging findings of methanol poisoning and detection of chronic stage nervous system damage: A case report

CAN¹,

ÖZTEKİN²

2023

J Exp Clin Med

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In this article, we presented the chronic neurological findings of an acute case of methanol intoxication due to the use of homemade alcohol. In the neurological examination performed 6 months after intoxication, bilateral vision loss, tremor, dysarthria, dysphagia, loss of taste sensation, and decrease in the Cognitive State Test score were detected. Peripheral polyneuropathy consistent with axonopathy was detected in the peripheral nerve conduction study, and optical neuropathy was detected in the examination of the pattern visual evoked potential. Brain magnetic resonance imaging revealed findings compatible with bilateral putaminal necrosis.

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Section: Discussionsupporting

confidence: 56%

Brain imaging findings of methanol poisoning and detection of chronic stage nervous system damage: A case report

CAN¹,

ÖZTEKİN²

2023

J Exp Clin Med

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“…The neurological manifestations of EG ingestion have been previously documented in case reports 1 – 3 10 – 12. Detailed sequential neurophysiological assessments were only available in very few cases.…”

Section: Discussionmentioning

confidence: 99%

Acute polyradiculoneuropathy with renal failure: mind the anion gap

Alzouebi

Sarrigiannis

Hadjivassiliou

2008

Journal of Neurology, Neurosurgery & Psychiatry

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We describe a 47-year-old male who presented with acute renal failure and later developed bilateral facial weakness, complete ophthalmoplegia, flaccid tetraparesis and diminished sensation in the extremities. Renal biopsy and urine toxicology were consistent with ethylene glycol intoxication. Sequential neurophysiological examinations revealed sensory nerve axonal loss, proximal motor nerve conduction block and a proximodistal type of axonal degeneration. Seven months after ingestion, the patient improved and was able to walk unaided but with residual bilateral facial weakness and distal sensory loss.

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“…Toxic conditions causing coma sometimes gives focal weakness. For example, ethylene glycol poisoning—characterised by a high anion gap acidosis with increased osmolar gap but without a distinctive breath odour—may be complicated by bilateral facial weakness and rarely a flaccid areflexic paralysis (with raised CSF protein, sometimes a pleocytosis); respiratory muscle weakness may begin a week after intoxication 41 42…”

Section: Introductionmentioning

confidence: 99%

Weakness in the intensive care unit

Walters

2022

Pract Neurol

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When asked to assess patients in an intensive care unit (ICU) who have respiratory muscle weakness, oropharyngeal weakness and a vulnerable airway, our immediate thought may be of Guillain-Barré syndrome or myasthenia gravis, but there are many other possible causes. For example, previously unrecognised chronic neurological conditions may decompensate and require ICU admission. Clinicians can use various clinical clues to help recognise them and need to understand how patterns of weakness reflect differing causes of reduced consciousness on ICU. Additionally, patients admitted to ICU for any reason may develop weakness during their stay, the most likely cause being ICU-acquired weakness. Assessing patients in ICU is challenging, hampered by physical barriers (machines, tubes), medication barriers (sedatives) and cognitive barriers (delirium, difficulty communicating). Nonetheless, we need to reach a clinical diagnosis, organise appropriate tests and communicate clearly with both patients and ICU colleagues.

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Severe sensorimotor polyradiculoneuropathy after ingestion of ethylene glycol

Cited by 8 publications

References 3 publications

Brain imaging findings of methanol poisoning and detection of chronic stage nervous system damage: A case report

Brain imaging findings of methanol poisoning and detection of chronic stage nervous system damage: A case report

Acute polyradiculoneuropathy with renal failure: mind the anion gap

Weakness in the intensive care unit

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