Severity of anxiety and work-related outcomes of patients with anxiety disorders

Erickson, Steven R.; Guthrie, Sally K.; VanEtten-Lee, Michelle; Himle, Joseph A.; Hoffman, Jody; Santos, Susana Ferrão; Janeck, Amy S.; Zivin, Kara; Abelson, James L.

doi:10.1002/da.20624

Cited by 67 publications

(94 citation statements)

References 27 publications

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“…In contrast, the degree of work productivity impairment in the past 7 days, as measured by the WPAI, reported in BED respondents (absenteeism: 9.59%±19.17%; presenteeism: 30.0%±31.64%) tended to be smaller in magnitude than in individuals with moderate to severe depressive symptoms (absenteeism + presenteeism: 46.9%–51.3%)18 or with moderate to severe anxiety (absenteeism: 16%±20%; presenteeism: 45%±30%) 19…”

Section: Discussionmentioning

confidence: 81%

Impact of binge eating disorder on functional impairment and work productivity in an adult community sample in the United States

et al. 2017

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SummaryAimThis study compared functioning and productivity in individuals meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM‐5) diagnostic criteria for binge eating disorder (BED) to those without BED.MethodsA sample of US adults from the National Health and Wellness Survey completed an Internet survey in October 2013. In addition to BED diagnostic criteria, the survey assessed functional impairment and productivity, respectively, using the Sheehan Disability Scale (SDS) and Work Productivity and Activity Impairment (WPAI) questionnaire. Differences between BED and non‐BED respondents were assessed using multivariate models controlling for factors, including age, sex and comorbidities.ResultsOf 22 397 respondents, 344 were categorised as BED respondents and 20 437 as non‐BED respondents. Compared with non‐BED respondents, BED respondents exhibited significantly (all P<.001) greater functional impairment on the SDS, as measured by mean±SD total (14.04±9.46 vs 3.41±6.36), work/school (3.86±3.62 vs 1.01±2.21), social life/leisure activities (5.29±3.49 vs 1.22±2.33) and family life/home responsibilities (4.89±3.44 vs 1.18±2.26) scores. Adjusted odds ratios (95% CIs) indicated that BED respondents were more impaired than non‐BED respondents on the work/school (4.24 [3.33–5.40]), social life/leisure activities (6.37 [4.97–8.15]) and family life/home responsibilities (5.76 [4.51–7.34]) domains of the SDS. On the WPAI, BED respondents reported significantly (all P<.001) higher percentages (mean±SD) of absenteeism (9.59%±19.97% vs 2.90%±12.95%), presenteeism (30.00%±31.64% vs 10.86%±20.07%), work productivity loss (33.19%±33.85% vs 12.60%±23.22%) and activity impairment (43.52%±34.36% vs 19.94%±27.22%) than non‐BED respondents.ConclusionsThe findings suggest individuals with BED experience considerable impairment in functioning and work productivity compared with individuals without BED.

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Section: Discussionmentioning

confidence: 81%

Impact of binge eating disorder on functional impairment and work productivity in an adult community sample in the United States

et al. 2017

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“…For example, depressed workers reported greater experienced difficulties in time management, mental, interpersonal and output job demands [2,3]. Other research showed that poor health and multiple health problems were associated with low work performance [4].…”

Section: Introductionmentioning

confidence: 99%

Prognostic Factors for Successful Work Functioning in the General Working Population

et al. 2012

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Purpose To help workers to stay at work in a healthy productive and sustainable way and for the development of interventions to improve work functioning, it is important to have insight in prognostic factors for successful work functioning. The aim of this study is to identify prognostic factors for successful work functioning in a general working population. Methods A longitudinal study (3 months follow-up) was conducted among the working population (N = 98). Work functioning was assessed with the Work Role Functioning Questionnaire 2.0 (WRFQ). The total score was categorized as follows: 0-90; [90 B95; and [95-100 (defined as 'successful work functioning'). Ordinal logistic regression analyses were performed to examine bivariate relationships between potential prognostic factors and the dependent variable (successful work functioning) to identify potential prognostic factors for the multivariate models (p \ 0.10). A stepwise approach was used to introduce the variables in the multiple ordinal regression analyses. Results Baseline work functioning and work ability were significant prognostic factors for successful work functioning at 3 months follow-up. No prospective associations were identified for psychological job demands and supervisor social support with successful work functioning. Conclusion To our knowledge this is the first longitudinal study to identify prognostic factors for successful work functioning in the general working population. High work ability is predictive for future successful work functioning, independent of baseline work functioning.

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“…1,2 It is characterized by recurrent, unprovoked and unpredictable panic attacks, followed by concern of subsequent attacks, resulting in a strong social and functional inhibition. 3,4 Estimates from family and twin studies ascribe a genetic contribution of approximately 40% to the disease etiology of the disorder. [5][6][7][8] However, the mechanism underlying PD is still unknown and presumably involves numerous susceptibility genes with major and/or minor effects.…”

Section: Introductionmentioning

confidence: 99%

A genome-wide study of panic disorder suggests the amiloride-sensitive cation channel 1 as a candidate gene

et al. 2011

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Panic disorder (PD) is a mental disorder with recurrent panic attacks that occur spontaneously and are not associated to any particular object or situation. There is no consensus on what causes PD. However, it is recognized that PD is influenced by environmental factors, as well as genetic factors. Despite a significant hereditary component, genetic studies have only been modestly successful in identifying genes of importance for the development of PD. In this study, we conducted a genome-wide scan using microsatellite markers and PD patients and control individuals from the isolated population of the Faroe Islands. Subsequently, we conducted a fine mapping, which revealed the amiloride-sensitive cation channel 1 (ACCN1) located on chromosome 17q11.2-q12 as a potential candidate gene for PD. The further analyses of the ACCN1 gene using singlenucleotide polymorphisms (SNPs) revealed significant association with PD in an extended Faroese case-control sample. However, analyses of a larger independent Danish case-control sample yielded no substantial significant association. This suggests that the possible risk alleles associated in the isolated population are not those involved in the development of PD in a larger outbred population.

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Severity of anxiety and work-related outcomes of patients with anxiety disorders

Abstract: Level of work performance was generally associated with severity of anxiety. Of the instruments tested, the WLQ and the WPAI questionnaire demonstrated acceptable validity and internal reliability.

Cited by 67 publications

References 27 publications

Impact of binge eating disorder on functional impairment and work productivity in an adult community sample in the United States

Impact of binge eating disorder on functional impairment and work productivity in an adult community sample in the United States

Prognostic Factors for Successful Work Functioning in the General Working Population

A genome-wide study of panic disorder suggests the amiloride-sensitive cation channel 1 as a candidate gene

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