Severity of diabetic retinopathy is associated with left ventricular diastolic dysfunction in patients with type 2 diabetes

Low-grade inflammation and endothelial dysfunction explain the association between retinopathy and left ventricular ejection fraction in men: an 8-year follow-up of the Hoorn Study

“…As in those studies (Aguilar et al, 2009;Cheung et al, 2007Cheung et al, , 2008Kurioka et al, 2013;Wong et al, 2005), adjustment for classical cardiovascular risk factors in our analyses did not influence the observed association between retinopathy and LV function. Most studies suggest that LGI, macro-or microvascular ED could be underlying mechanisms to both retinopathy and heart disease.…”

“…Our findings extend previous studies which reported significant associations of retinopathy with LV dysfunction (Aguilar et al, 2009;Kurioka et al, 2013), coronary heart disease (Cheung et al, 2007) or HF (Cheung et al, 2008;Wong et al, 2005). As in those studies (Aguilar et al, 2009;Cheung et al, 2007Cheung et al, , 2008Kurioka et al, 2013;Wong et al, 2005), adjustment for classical cardiovascular risk factors in our analyses did not influence the observed association between retinopathy and LV function.…”

“…None of the previous studies (Aguilar et al, 2009;Cheung et al, 2007Cheung et al, , 2008Kurioka et al, 2013;Wong et al, 2005) stratified for sex, and to our knowledge, there is no other literature describing sex differences in the association between retinopathy and LV function. Although (predominantly) not significant, we showed that the association between retinopathy and LV function differed among ⁎ p value b 0.05.…”

“…Studies on the association between retinopathy and LV function, in which objective measures like echocardiography are used, are rare and exist on a cross-sectional base only (Aguilar et al, 2009;Kurioka, Ose, Fukuma, & Yoshimoto, 2013). Furthermore, the potential confounding role of LGI and micro-or macrovascular ED dysfunction has, to our knowledge, not yet been investigated.…”

Morbidity and Mortality Patterns Among Admitted Patients With Diabetes : A Hospital Based Study From North India.

“…Half of all patients (50%) had diabetic retinopathy in the present study,which is not same as findings of Jean Claude Mbanya et al [46] who reported only 18% diabetics with retinopathy and Eugene Sobngwi et al [46] also observed background retinopathy in only 18% and cataract in 14% and these were the most common eye complications in diabetics as reported in other studies [30], [45], [57] also.In our study, 20% of patients had cataract. In the present study,more than half (52%) had neuropathy, that was consistent with the study of Jean Claude Mbanya et al [46] who reported neuropathy in 48% and the study by Upinder K Dhand [58] who showed that 60% of peripheral neuropathy was due to diabetes, however, the results were not same as reported by Pradeepa R et al [59] where only 26.1% had diabetic neuropathy.…”