Severity of erectile dysfunction in married impotent patients: Interrelationship with anthropometry, hormones, metabolic profiles and lifestyle

Abstract

Objective: This study was designed to evaluate the effects of risk factors for erectile dysfunction (ED) or cardiovascular disease on the disease severity in impotent men. Methods: A total of 87 men, 25-75 years old (mean age, 53.4) were included in the study. Patients were evaluated with anthropometry, hormones, metabolic profiles and lifestyle. Baseline erectile function (EF) was evaluated using the International Index of Erectile Function (IIEF). The severity of ED was classified into the following four grades based on the six-item EF domain of the IIEF: severe (6-10); moderate (11-16); mild to moderate (17-21); and mild (22-25). Patients were deemed to have metabolic syndrome (MS) if they had three or more of five criteria according to National Cholesterol Education Program, with some modification. Results: Of 87 patients, 15 patients (17.2%) had mild , 11 (12.6%) had mild to moderate, 33 (37.9%) had moderate and 28 (32.3%) had severe ED. There was no correlation between scores of IIEF or EF domain and continuous parameters. On the multivariate model used , hypertensive patients had 26-fold higher risk (odds ratio, 26.195; 95% confidence interval, 1.463-46.072; P = 0.027) of severe ED than those without hypertension. Other factors were not significant. Conclusion:The results of the study indicate that MS might not influence the severity of ED in impotent men. However, our findings suggest that hypertension plays a role in the disease severity in these patients.

Surveillance of cardiovascular risk factors for outpatients in different erectile dysfunction severity

“…These observations are consistent with those of Paick et al 26 who concluded that MS was not correlated with ED severity. In our study, systolic blood pressure showed an inversely impact to the ED severity.…”

“…Paick et al 26 concluded that MS may not influence the severity of ED in impotent men. In our study, the IIEF scores were relatively lower in patients with MS than in those without MS.…”

“…17 Questions 1-5 and 15 of the IIEF constitute the erectile function domain, which is used to assess global erectile function. Scoring the IIEF domain of erectile function allowed the classification of each patient as follows: absent of ED (26)(27)(28)(29)(30), mild ED (17)(18)(19)(20)(21)(22)(23)(24)(25), moderate ED (11)(12)(13)(14)(15)(16) and severe ED (0-10).…”

Association between metabolic syndrome and sexual dysfunction among men with clinically diagnosed diabetes

“…The mediating effect of raised blood pressure between MetS and SD is in conformity with previous studies [34,35]. Increased sympathetic tone in raised blood pressure combined with endothelial dysfunction in MetS, or other organic status, are the most plausible pathway for inducing SD.…”

The Relationship between Neovascular Age-Related Macular Degeneration and Erectile Dysfunction

“…Lifestyle factors such as smoking, high alcohol intake, poor diet, and physical inactivity may also influence sexual dysfunction [29, 30]. Interestingly, these observations were not corroborated by Paick et al who did not find a significant relationship between ED severity and metabolic syndrome, BMI, hormones, lifestyle [31]. Smith et al studied an association between BMI and sexual satisfaction.…”