Sex and age differences in prevalence and risk factors for prediabetes in Mexican-Americans

Abstract

Over 1/3 of Americans have prediabetes, while 9.4% have type 2 diabetes. The aim of our study was to estimate the prevalence of prediabetes in Mexican Americans, with known 28.2% prevalence of type 2 diabetes, by age and sex and to identify critical sociodemographic and clinical factors associated with prediabetes. Methods: Data were collected between 2004 and 2017 from the Cameron County Hispanic Cohort in Texas. Weighted crude and sex-and age-stratified prevalences were calculated. Survey weighted logistic regression analyses were conducted to identify risk factors for prediabetes. Results: The prevalence of prediabetes (32%) was slightly higher than the alarmingly high rate of type 2 diabetes (28.2%). Hispanic men had the highest overall (37.8%) and highest age stratified prevalence of prediabetes. Males had higher odds of prediabetes than females 1.56 (1.19, 2.06), controlling for the effect of family history of diabetes, age, BMI, and high-density lipoprotein. Family history of diabetes was a strong independent risk factor for prediabetes in all men, and in men and women in the age group 40-64 years. Elevated triglycerides (p = 0.003) was an independent risk factor for men and women in the age group 18-39 years. Conclusions: Despite the very high prevalence of type 2 diabetes, prediabetes prevalence among Mexican Americans is only marginally less than national prediabetes rates. This suggests that progression to type 2 diabetes is more rapid and occurs earlier than nationally. Earlier screening and interventions for prediabetes, especially for men, are necessary to slow the transition to diabetes.

Impact of Work and Recreational Physical Activity on Prediabetes Condition among U.S. Adults: NHANES 2015–2016

“…In France the prevalence was 28.6% using the ADA criteria [ 6 ]. In the U.S., a study on Mexican Americans reported a prevalence of 32% [ 7 ]. Meanwhile, in Peru, this value was 53.6% [ 8 ].…”

A Prediction Model for Prediabetes Risk in Middle-Aged and Elderly Populations: A Prospective Cohort Study in China

“…Diabetes pathogenesis involves interactions between genes and the environment. Factors influencing prediabetes include age [ 8 , 9 ], educational attainment [ 9 ], marital status [ 9 ], hypertension [ 10 ], dyslipidemia [ 11 ], gestational diabetes, body mass index (BMI) [ 9 , 12 ], WC [ 12 ], FHD [ 13 ], diet patterns [ 14 ], and 1-hour plasma glucose levels [ 15 ]. In Japan, a prognostic model based on six variables was built to predict the incidences of type 2 diabetes mellitus and prediabetes in a healthy population [ 16 ].…”

Social distancing and testing as optimal strategies against the spread of COVID-19 in the Rio Grande Valley of Texas

“…According to the U.S. Census Bureau, the estimated RGV population was 1,305,782 with more than 90% of the population as Hispanic or Latino on July 1, 2019 ( The United States Census Bureau, 2020 ). Several studies have characterized the Mexican American population living in this region as having high poverty rates, low educational attainment, low health literacy, lack of health care coverage, extremely high rates of obesity, type 2 diabetes, metabolic complications, cardiovascular diseases and other diseases ( Laing et al, 2015 ; Vatcheva, Fisher-Hoch, Reininger, & McCormick, 2020 ) .…”