2007
DOI: 10.1152/ajprenal.00408.2006
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Sex-differential expression of ornithine aminotransferase in the mouse kidney

Abstract: The mouse kidney expresses the gene of ornithine aminotransferase (Oat). Previous works suggest that Oat is differentially expressed in female and male mouse kidney (Alonso E, Rubio V. Biochem J 259: 131-138, 1989; Levillain O, Diaz JJ, Blanchard O, Dechaud H. Endocrinology 146: 950-959, 2005; Manteuffel-Cymborowska M, Chmurzynska W, Peska M, Grzelakowska-Sztabert B. Int J Biochem Cell Biol 27: 287-295, 1995; Natesan S, Reddy SR. Comp Biochem Physiol B Biochem Mol Biol 130: 585-595, 2001; Yu H, Yoo PK, Aguirre… Show more

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Cited by 7 publications
(9 citation statements)
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“…Consequently, testosterone naturally controls and down-regulates the expression of OAT gene in the male mouse kidney. Furthermore, orchidectomy completely abolished the sexual dimorphism of the renal expression of OAT gene (Levillain et al, 2007). The present findings confirm these statements.…”
Section: Discussionsupporting
confidence: 89%
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“…Consequently, testosterone naturally controls and down-regulates the expression of OAT gene in the male mouse kidney. Furthermore, orchidectomy completely abolished the sexual dimorphism of the renal expression of OAT gene (Levillain et al, 2007). The present findings confirm these statements.…”
Section: Discussionsupporting
confidence: 89%
“…Constantly, OAT activity was more than three-fold higher in female than in male mouse kidney. The sex-differential OAT activity found in the present results is in good agreement with published data (Levillain et al, 2007;Ventura et al 2009). Closed circles: female mouse kidney and closed triangles: male mouse kidney.…”
Section: Oat Activity Assaysupporting
confidence: 93%
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