Sex-related differences in the impact of nutritional status on in-hospital mortality in acute coronary syndrome: A retrospective cohort study

Kwaśny, Adrian; Łokieć, Katarzyna; Uchmanowicz, Bartosz; Młynarska, Agnieszka; Smereka, Jacek; Czapla, Michał

doi:10.1016/j.numecd.2023.06.010

Cited by 6 publications

(6 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, differences in the nutritional status of patients with CVD vary according to sex. In patients with acute myocardial infarction, the risk of malnutrition screened by the “Nutritional Risk Screening 2002 (NRS-2002)” significantly predicted in-hospital mortality in female patients but not in male patients ( 38 ) indicating the possibility of malnutrition as a sex-specific factor in predicting disease risk or mortality. Recent studies have indicated that the risk of malnutrition assessed by the GNRI accurately predicts disease risk and cardiovascular mortality ( 20 , 39–41 ), and these findings appear consistent with those of a previous study assessing a single individual indicator of malnutrition ( 22 , 33 , 34 ).…”

Section: Discussionmentioning

confidence: 99%

“…A randomized clinical trial and a cross-sectional study of community-dwelling older adults found that supplementing or enhancing their energy status and protein consumption improved their nutritional status ( 63 , 64 ) and reduced disease prevalence ( 65 ). Moreover, sex differences exist in the association of malnutrition with heart disease ( 38 ) and cardiovascular outcomes in response to nutritional supplements or dietary patterns of patients ( 66 ). However, discrepant results indicate that being underweight and the risk of malnutrition are directly associated with the odds of in-hospital mortality in men but not in women ( 67 ).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The ability of the geriatric nutritional risk index to predict the risk of heart diseases in Korean adults: a Korean Genome and Epidemiology Study cohort

Park,

2023

Front. Nutr.

View full text Add to dashboard Cite

IntroductionThe predictive ability of nutritional risk index on cardiovascular outcomes in middle-aged and non-hospitalized adults has not yet been reported. This study investigated whether the Geriatric Nutritional Risk Index (GNRI), an index for assessing the risk of developing malnutrition, could predict heart disease in middle-aged Korean adults.MethodsThe cohort used in this study consisted of 3,783 participants selected from 10,030 Korean adults who participated in the Ansan-Ansung cohort study as part of the Korean Genome and Epidemiology Study. The GNRI was determined based on serum albumin level, proportion of current weight, and ideal body weight. Participants were then divided into two groups: GNRI ≤98 and > 98, which corresponded to the risk of malnutrition and normal, respectively. The major outcome of this study was coronary artery disease (CAD) or congestive heart failure (CHF) during a 15-year-follow period.ResultsDuring the follow-up period spanning 2004–2018, 136 events of heart disease occurred. Using a Kaplan–Meier analysis, event-free rates were found to be associated with 90.5% on a GNRI ≤98 and 96.6% on a GNRI >98 (p < 0.0009). GNRI ≤98 showed a 3.2-fold (hazard ratio, 3.22; 95% credit interval, 1.49–6.96; p = 0.0029) increase in the incidence of heart disease, including CAD or CHF, compared with GNRI >98, after controlling for potential confounders.ConclusionMalnutrition risk confers a significantly increased risk for heart disease in middle-aged Koreans. Further studies with larger cohorts are needed to verify the efficacy of the GNRI in predicting disease risk in adults with pre-disease.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The ability of the geriatric nutritional risk index to predict the risk of heart diseases in Korean adults: a Korean Genome and Epidemiology Study cohort

Park,

2023

Front. Nutr.

View full text Add to dashboard Cite

show abstract

“…Lifestyle factors play a significant role in this regard, and economic, social, and cultural aspects also significantly influence life satisfaction in older adults [11]. Identifying factors conducive to health and well-being in the aging population is essential to address the increasing prevalence of chronic diseases and rising healthcare costs, thereby enhancing life satisfaction [12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Satisfaction with Life and Health Behaviours in Pre-Seniors and Seniors: A Cross-Sectional Cohort Study

Głowacka,

Dykowska,

Gasik

et al. 2024

Sustainability

View full text Add to dashboard Cite

Background: Satisfaction with life is considered the best indicator of the quality of life of older people and is commonly used as an indicator of adaptation and successful aging. The objective of this study is to evaluate the quality of life and health among pre-seniors and seniors in Płock, Poland, focusing specifically on the interplay between life satisfaction and health outcomes. Methods: The study encompassed a total of 2040 individuals, categorized as pre-seniors and seniors. A diagnostic survey method was employed, utilizing a questionnaire that gathered sociodemographic data and incorporated two standardized psychometric scales: the Satisfaction with Life Scale (SWLS) and the Health Behaviours Inventory (HBI). Results: A majority of respondents demonstrated high levels of life satisfaction, with 1272 people (62.4%) scoring in the high range. In contrast, a smaller group, consisting of 299 respondents (14.7%), reported low satisfaction levels. Notably, men exhibited higher life satisfaction than women (p < 0.001). Additionally, a statistically significant but low correlation was found between the age of respondents and various aspects of the health behaviour index. This includes preventive behaviours (p < 0.001, r = 0.105), health practices (p < 0.001, r = 0.243), proper eating habits (p = 0.004, r = 0.063), and a positive mental attitude (p < 0.001, r = 0.098). These findings underline the complex interplay between age, life satisfaction, and health behaviours among the senior population. Conclusions: High life satisfaction and average to high levels of health behaviours were observed in our study, varying with gender and age. Individuals aged 61–75 reported the highest life satisfaction, whereas those aged 76–90 exhibited the most robust health behaviours. These results underscore the need for age- and gender-specific health policies and programs supporting sustainable aging, aligning with the Sustainable Development Goals. Further national research is essential to comprehensively explore these trends and support global well-being initiatives for aging populations.

show abstract

“…In this regard, two recent studies revealed sex-related disparities in the role of nutrition. Specifically, one study found that, in patients with acute coronary syndrome, malnutrition was a predictor of in-hospital mortality only in women [ 16 ], while the other study found that, in patients with heart failure (HF), malnutrition was independently associated with the odds of in-hospital mortality in men, but not in women [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Adherence to the Mediterranean Diet in Preventing Major Cardiovascular Events in Patients with Ischemic Heart Disease: The EVA Study

et al. 2023

View full text Add to dashboard Cite

Background: Adherence to healthy dietary patterns, such as the Mediterranean diet (Med-diet), is recommended for the maintenance of cardiovascular health. The determinants for adherence to Med-diet and its importance in secondary cardiovascular disease prevention are still unclear. The aim of the study was to evaluate the influence of sex- and psycho-socio-cultural (i.e., gender-related) factors on Med-diet adherence and its role in preventing major cardiovascular events (MACEs) in patients with ischemic heart disease (IHD). Methods: Med-diet adherence was evaluated among 503 consecutive adults with IHD. MACEs were collected during a long-term follow-up. Results: Male Bem Sex-Role Inventory score (i.e., male personality traits) and physical functional capacity were associated with higher adherence, while cohabitation with a smoker and physical inactivity with poorer adherence. During a median follow-up of 22 months, 48 participants experienced MACEs (17.5%, 8.1%, and 3.9% of patients with low, medium, and high adherence, respectively; p = 0.016). At multivariate Cox--regression analysis, a greater adherence remained inversely associated with MACEs (HR: 0.49; 95% CI: 0.29–0.82; p = 0.006) after adjusting for confounding factors. Conclusion: The study suggests that gender-related factors have a role in maintaining a healthy dietary pattern. Improving Med-diet adherence may lower the risk of recurring cardiovascular events.

show abstract

Sex-related differences in the impact of nutritional status on in-hospital mortality in acute coronary syndrome: A retrospective cohort study

Cited by 6 publications

References 47 publications

The ability of the geriatric nutritional risk index to predict the risk of heart diseases in Korean adults: a Korean Genome and Epidemiology Study cohort

The ability of the geriatric nutritional risk index to predict the risk of heart diseases in Korean adults: a Korean Genome and Epidemiology Study cohort

Satisfaction with Life and Health Behaviours in Pre-Seniors and Seniors: A Cross-Sectional Cohort Study

Adherence to the Mediterranean Diet in Preventing Major Cardiovascular Events in Patients with Ischemic Heart Disease: The EVA Study

Contact Info

Product

Resources

About