Sex-specific associations between serum uric acid levels and risk of hypertension for different diagnostic reference values of high blood pressure

Salim, Anwar Ahmed; Kawasoe, Shin; Kubozono, Takuro; Ojima, Satoko; Kawabata, Takeko; Ikeda, Yoshiyuki; Miyahara, Hironori; Tokushige, Koichi; Ohishi, Mitsuru

doi:10.1038/s41440-023-01535-0

Cited by 4 publications

(2 citation statements)

References 52 publications

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“…However, women are more vulnerable to developing hypertension than men. 39,40 Moreover, heightened UA levels in females are linked with an elevated risk of arterial sclerosis and atrial fibrillation. 41,42 Moreover, it is noteworthy that elevated levels of UA were observed to correlate with heightened uptake of dopamine transporter in the putamen among female patients diagnosed with early Parkinson's disease.…”

Section: Discussionmentioning

confidence: 99%

Association between serum uric acid levels and lung function in the NHANES cohort (2007–2012): A cross‐sectional analysis of a diverse American population

Kang,

Xi,

et al. 2024

Int J of Rheum Dis

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BackgroundHyperuricemia has been linked to various health conditions. However, the relationship between uric acid (UA) levels and lung function remains debated.MethodsIn a cross‐sectional study of 6750 participants aged 20–69 from NHANES, we assessed UA levels and lung function (FVC and FEV1). We conducted regression analyses while adjusting for potential confounders.ResultsAfter accounting for factors like age, sex, BMI, smoking, and more, we found a negative association between UA FVC and FEV1. Specifically, for every 0.1 mg/dL increase in UA, FEV1 decreased by 15.265 mL, and FVC decreased by 24.46 mL. No association was observed with FEV1/FVC. Subgroup analyses revealed similar negative correlations among various groups, particularly in non‐Hispanic Black females under 60.ConclusionSerum UA levels are inversely associated with FEV1 and FVC in the American population, with a notable impact on non‐Hispanic Black females under 60.

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Section: Discussionmentioning

confidence: 99%

Association between serum uric acid levels and lung function in the NHANES cohort (2007–2012): A cross‐sectional analysis of a diverse American population

Kang,

Xi,

et al. 2024

Int J of Rheum Dis

View full text Add to dashboard Cite

show abstract

“…In this month's issue, we provide three papers related to clinical examination and organ damage for hypertension. Salim et al reported the association between serum uric acid (UA) level and a risk of future hypertension according to sex [7]. In men, the threshold of UA level for a risk of hypertension was 6.5 mg/dl, and that in women was 6.0 mg/dl.…”

mentioning

confidence: 99%