Sex-Specific Outcomes After Coronary Intravascular Lithotripsy: A Patient-Level Analysis of the Disrupt CAD Studies

Hussain, Yasin; Kearney, Kathleen; Abbott, J. Dawn; Kereiakes, Dean J.; Mario, Carlo Di; Saïto, Shigeru; Cristea, Ecaterina; Riley, Robert F.; Fajadet, Jean; Shlofmitz, Richard; Ali, Ziad A.; Klein, Andrew J.; Price, Matthew J.; Hill, Jonathan; Stone, Gregg W.; Lansky, Alexandra J.

doi:10.1016/j.jscai.2021.100011

Cited by 4 publications

(10 citation statements)

References 42 publications

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“…No entanto, a litotripsia intravascular apresenta complicações angiográficas, segurança e eficácia semelhantes em mulheres e homens. 65,278 10.5. Terapia Farmacológica Adjunta Embora estudos randomizados sugiram benefícios semelhantes da terapia antitrombótica adjunta para doença coronariana em ambos os sexos, mulheres recebem menos frequentemente o tratamento proposto nas diretrizes.…”

Section: Aterectomia Rotacional E Litotripsia Intravascularunclassified

“…No entanto, a litotripsia intravascular apresenta complicações angiográficas, segurança e eficácia semelhantes em mulheres e homens. 65 , 278 …”

Section: 4 Tratamento Percutâneo Da Doença Aterotrombótica Coronária ...unclassified

“…However, intravascular lithotripsy has angiographic complications, safety, and efficacy similar in women and men. 65 , 278 …”

Section: 4 Percutaneous Treatment Of Coronary Atherothrombotic Diseas...mentioning

confidence: 99%

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Posicionamento sobre Doença Isquêmica do Coração – A Mulher no Centro do Cuidado – 2023

Oliveira¹,

Almeida²,

Rassi³

et al. 2023

Arquivos Brasileiros De Cardiologia

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Section: Aterectomia Rotacional E Litotripsia Intravascularunclassified

“…No entanto, a litotripsia intravascular apresenta complicações angiográficas, segurança e eficácia semelhantes em mulheres e homens. 65 , 278 …”

Section: 4 Tratamento Percutâneo Da Doença Aterotrombótica Coronária ...unclassified

See 1 more Smart Citation

Posicionamento sobre Doença Isquêmica do Coração – A Mulher no Centro do Cuidado – 2023

Oliveira¹,

Almeida²,

Rassi³

et al. 2023

Arquivos Brasileiros De Cardiologia

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show abstract

“…Disrupt CAD I-IV studies evaluated IVL-facilitated stenting for de novo severely calcified coronary artery lesions in a total of 628 patients (23% women) with stable or unstable angina or silent ischemia. Sex-based analysis of these studies showed no difference in 30-day MACE (composite of cardiac death, MI, or TVR), and similar success rate in stent delivery with ≤ 30% residual in-stent stenosis in women compared to men [ 62 ].…”

Section: Technical Aspect Of Pcimentioning

confidence: 99%

Percutaneous Coronary Interventions in Women

Joodi,

Palimar,

Press

2023

Curr Atheroscler Rep

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Purposeof Review Cardiovascular disease is the leading cause of morbidity and mortality among women globally. Numerous studies show ongoing disparities in diagnosis, management, and outcomes of ischemic heart disease in women compared to men. We aim to review the factors contributing to sex-based differential outcomes of percutaneous coronary interventions in women. Recent Findings Hormonal influence on coronary arteries and progression of atherosclerosis in women results in distinct coronary plaque characteristics and unique pathological process such as spontaneous coronary artery dissection and myocardial infarction with non-obstructive coronary arteries. During the presentation of acute coronary syndromes, women are older and have higher burden of comorbidities, with higher short- and long-term mortality. Summary Awareness of differences in vascular biology and unique risk factors for cardiovascular disease in women is essential for sustained improvement in cardiovascular mortality. Better representation of women in trials is crucial to address the gaps in knowledge and allow for individualized treatment approaches in women.

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“…Yasin Hussain, MD, and colleagues report sex-based outcomes after coronary IVL in a large patient-level pooled analysis of the 4 prospective Disrupt CAD studies. 3 Women undergoing percutaneous coronary intervention of severely calcified lesions are particularly vulnerable to poor acute and long-term outcomes, including more flow-limiting dissections, perforations, and a higher rate of mortality in the longer term compared with men. The evidence presented in the current issue with IVL-facilitated stenting of severely calcified lesions demonstrates low rates of dissection and perforation and similar safety and efficacy in women and men.…”

mentioning

confidence: 99%

A Warm Welcome to The First Issue of JSCAI

Lansky¹

2022

Journal of the Society for Cardiovascular Angiography & Int

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Sex-Specific Outcomes After Coronary Intravascular Lithotripsy: A Patient-Level Analysis of the Disrupt CAD Studies

Cited by 4 publications

References 42 publications

Posicionamento sobre Doença Isquêmica do Coração – A Mulher no Centro do Cuidado – 2023

Posicionamento sobre Doença Isquêmica do Coração – A Mulher no Centro do Cuidado – 2023

Percutaneous Coronary Interventions in Women

A Warm Welcome to The First Issue of JSCAI

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