Sexual and Demographic Risk Factors for Herpes Simplex Virus Type 2 According to Schooling Level Among Mexican Youths

Background The degree of effectiveness of condoms in preventing the transmission of herpes simplex virus 2 (HSV-2), is uncertain. We performed a large pooled analysis to address this question. Methods We identified prospective studies with individual-level condom use data and laboratory-defined HSV-2 acquisition. Six studies were identified through a review of publications through 2007: three candidate HSV-2 vaccine studies, an HSV-2 drug study, an observational STD incidence study and a behavioral STD intervention study. Study investigators provided us individual-level data to perform a pooled analysis. Effect of condom use was modeled using a continuous percent of sex acts during which a condom was used and, alternatively, using absolute number of unprotected sex acts. Results A total of 5384 people who were HSV-2 negative at baseline contributed 2,040,894 follow-up days. 415 persons acquired laboratory-documented HSV-2 during follow-up. Consistent (100%) condom users had a 30% lower risk of HSV-2 acquisition compared to those who never used condoms (hazard ratio: 0.70; 95 percent confidence interval: 0.40, 0.94; p = 0.01). Risk for HSV-2 acquisition increased steadily and significantly with each unprotected sex act (hazard ratio: 1.16; 95 percent confidence interval: 1.08, 1.25); p < 0.001). Condom effectiveness did not vary by gender. Conclusions This is the largest analysis using prospective data to assess the effect of condoms in preventing HSV-2 acquisition. Although the magnitude of protection was not as large as has been observed with other STIs, we found that condoms offer moderate protection against HSV-2 acquisition in men and women.

show abstract

A Pooled Analysis of the Effect of Condoms in Preventing HSV-2 Acquisition

Martin¹,

Krantz²,

Gottlieb³

et al. 2009

Arch Intern Med

124

View full text Add to dashboard Cite

show abstract

A quasi‐experimental evaluation of parents as sexual health educators resulting in delayed sexual initiation and increased access to condoms ^⋆

Campero¹,

Walker²,

Atienzo³

et al. 2010

Journal of Adolescence

View full text Add to dashboard Cite

ObjectiveTo evaluate the effectiveness of an educational intervention for parents of first year high school students in the State of Morelos, Mexico, whose aim was to impact adolescents’ sexual behavior, knowledge and access to contraception.Material and methodsQuasi‐experimental prospective study with eleven control and eleven intervention schools using self‐administered questionnaires for parents and adolescents pre‐ and post‐intervention. Parent–child dyads in the control and intervention schools were matched according to parents’ propensity score; the average treatment effect (ATE) was estimated for adolescent’s outcome variables.ResultsAt follow‐up, we found significant differences for adolescents in the intervention schools: 6.8% delayed initiation of sexual intercourse, 14.4% had correct knowledge about emergency contraception (EC), and 164% reported having received condoms from their parents, when comparing with students in control schools.ConclusionsOur results suggest that parent‐focused interventions could be an innovative and effective strategy to promote adolescents sexual health.

show abstract

Sexual Behavior and Herpes Simplex Virus 2 Infection in College Students

Sánchez-Alemán

Conde-Glez

Gayet³

et al. 2005

Archives of Medical Research

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Sexual and Demographic Risk Factors for Herpes Simplex Virus Type 2 According to Schooling Level Among Mexican Youths

Cited by 14 publications

References 24 publications

A Pooled Analysis of the Effect of Condoms in Preventing HSV-2 Acquisition

A Pooled Analysis of the Effect of Condoms in Preventing HSV-2 Acquisition

A quasi‐experimental evaluation of parents as sexual health educators resulting in delayed sexual initiation and increased access to condoms ^⋆

Sexual Behavior and Herpes Simplex Virus 2 Infection in College Students

Contact Info

Product

Resources

About

Sexual and Demographic Risk Factors for Herpes Simplex Virus Type 2 According to Schooling Level Among Mexican Youths

Cited by 14 publications

References 24 publications

A Pooled Analysis of the Effect of Condoms in Preventing HSV-2 Acquisition

A Pooled Analysis of the Effect of Condoms in Preventing HSV-2 Acquisition

A quasi‐experimental evaluation of parents as sexual health educators resulting in delayed sexual initiation and increased access to condoms ⋆

Sexual Behavior and Herpes Simplex Virus 2 Infection in College Students

Contact Info

Product

Resources

About

A quasi‐experimental evaluation of parents as sexual health educators resulting in delayed sexual initiation and increased access to condoms ^⋆