Sexual dysfunction in female patients of reproductive age group with recurrent urinary tract infection—a cross-sectional study

Mondal, Soumya; NOORI, DR MD TAQUEDIS; PAL, DR DILIP KUMAR

doi:10.1016/j.xagr.2022.100083

Cited by 4 publications

(4 citation statements)

References 23 publications

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“…Women of reproductive age experiencing recurrent UTIs reported lower female sexual function index (FSFI) scores, indicative of sexual dysfunction, in comparison to those without recurrent UTIs (59.4% versus 22.6%, respectively). This association is further corroborated by elevated female sexual distress scale (FSDS) scores, suggesting a profound impact on sexual distress [ 19 ]. Additionally, specific predictors of symptomatic UTIs identified among nursing students, including rural background, insufficient water intake, and inadequate toilet habits, emphasize the critical role of environmental and lifestyle factors [ 17 ].…”

Section: Reviewmentioning

confidence: 98%

“…The selected articles contributed to the overall understanding of UTIs in this specific population. Among the six studies included, which covered a total of 580,455 females, three were cross-sectional studies [ 14 , 16 , 19 ], and one each was an observational study [ 15 ], a cohort study [ 17 ], and a case-control study [ 18 ], respectively.…”

Section: Reviewmentioning

confidence: 99%

“…This evaluation aimed to determine the methodological quality and potential biases within each study to ensure the reliability and validity of our findings. The risk of bias assessment indicates that the majority of selected studies exhibit a "low to moderate" risk of bias [ 14 , 15 , 17 - 19 ], with one study having a "low" risk of bias rating [ 16 ]. This suggests that while there is generally a good level of methodological rigor and reporting clarity among the studies, the studies provide valuable insights into the correlates of UTIs among women in India, contributing to a nuanced understanding of this significant health issue, albeit with a degree of caution due to the potential biases identified in Table 3 [ 14 - 19 ].…”

Section: Reviewmentioning

confidence: 99%

“…Moreover, the impact of recurrent UTIs on sexual function, where nearly 60% of affected women experienced sexual dysfunction, illuminates the profound implications of UTIs beyond the immediate physical discomfort. This association with sexual dysfunction underscores the broader repercussions on women's sexual health and overall quality of life, amplifying the call for holistic clinical management strategies that address both the infection and its secondary impacts [ 19 ].…”

Section: Reviewmentioning

confidence: 99%

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Correlates of Urinary Tract Infections Among Women of Reproductive Age in India: A Systematic Review

Mavi,

Rathi,

Shannawaz

et al. 2024

Cureus

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Urinary tract infections (UTIs) are a significant health concern globally, with a pronounced impact on women's health in India. This systematic literature review aims to elucidate the factors associated with UTIs among women of reproductive age in India and focus on demographic, behavioral, and physiological factors to inform targeted public health and clinical interventions. A systematic literature search was conducted on PubMed and Google Scholar using specific MeSH terms and preferred reporting items for systematic literature reviews and meta-analyses (PRISMA) guidelines to investigate the correlates of UTIs among Indian women. Studies were selected based on their relevance to the correlates of UTIs among Indian women, including risk factors, prevention strategies, and treatment outcomes. The review identified a significant prevalence of UTIs among pregnant women, with Escherichia coli being the most common causative agent. Younger women, particularly those pregnant, were found to be at a higher risk, likely due to physiological changes during pregnancy and increased sexual activity. Behavioral and lifestyle factors, such as inadequate water intake and poor sanitation practices, were strongly associated with increased risks for UTIs. Factors that increase the risk of UTIs in women include frequent sexual activity, involvement with a new sexual partner, spermicide use that can potentially alter vaginal pH and impact its bacterial composition, and vulvovaginal atrophy. Additionally, nearly 60% of women globally with recurrent UTIs experienced sexual dysfunction, indicating the broader implications of UTIs on women's sexual health and quality of life. UTIs among women in India are influenced by a complex interplay of factors. There is a critical need for enhanced public health initiatives focusing on sanitation, hydration, and hygiene, alongside holistic clinical management strategies that address both the infection and its broader health impacts. Future research should aim at developing innovative prevention and treatment strategies, with a particular focus on high-risk groups such as pregnant women, to mitigate the burden of UTIs in India.

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Section: Reviewmentioning

confidence: 98%

Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

See 2 more Smart Citations

Correlates of Urinary Tract Infections Among Women of Reproductive Age in India: A Systematic Review

Mavi,

Rathi,

Shannawaz

et al. 2024

Cureus

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Recurrent UTI in Women–Risk Factors and Management

Lazarus,

Gupta

2024

Infectious Disease Clinics of North America

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Oral preparation of hyaluronic acid, chondroitin sulfate, N-acetylglucosamine, and vitamin C improves sexual and urinary symptoms in participants with recurrent urinary tract infections: a randomized crossover trial

Boeri,

De Lorenzis,

Lucignani

et al. 2024

The Journal of Sexual Medicine

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Background Intravesical instillation of hyaluronic acid (HA) has been associated with reduced sexual dysfunction in participants with recurrent urinary tract infections (rUTIs), but the efficacy of an oral treatment has never been investigated. Aim To investigate the efficacy of an oral preparation of HA, chondroitin sulfate, N-acetylglucosamine, and vitamin C in improving sexual and urinary symptoms in a cohort of reproductive-age participants with rUTI. Methods In a monocentric randomized crossover pilot trial, participants with rUTI who were referred to our institute between March 2022 and April 2023 were randomized 1:1 in 2 groups: intervention vs control. All participants had an oral preparation of cranberry, D-mannose, propolis extract, turmeric, and Boswellia twice a day for 3 months. The intervention group also included an oral preparation of HA, chondroitin sulfate, N-acetylglucosamine, and vitamin C once a day for 3 months. Crossover of treatment occurred at 3 months for an additional 3 months. At baseline and 3 and 6 months, participants were evaluated clinically and with the International Prostate Symptom Score (IPSS) and Female Sexual Function Index (FSFI). Descriptive statistics and logistic regression models tested the impact of the intervention on urinary and sexual symptoms at each follow-up assessment. Outcomes Improvement in sexual and urinary symptoms as measured by the FSFI and IPSS. Results Overall, 27 (54%) participants had an FSFI score <26.5 at enrollment. At 3 months, FSFI scores were higher in the intervention group vs control (P < .001), but IPSS scores were lower (P = .03). After crossover of treatment, FSFI and IPSS scores remained stable in the intervention group. However, after crossover, the control group showed a significant improvement in IPSS and FSFI scores (all P < .01) vs the 3-month assessment. At last follow-up, urinary and sexual symptoms were comparable between groups. In logistic regression analyses, the intervention group was associated with early improvement in sexual symptoms (odds ratio, 3.9; P = .04) and urinary symptoms (odds ratio, 5.1; P = .01) after accounting for clinical confounders. Clinical Implications Combination treatment with HA, chondroitin sulfate, N-acetylglucosamine, and vitamin C is effective if started immediately or even after a few months from symptoms in participants with rUTI. Strengths and Limitations The main limitation is the lack of long-term follow-up. Conclusion The oral formulation of HA, chondroitin sulfate, N-acetylglucosamine, and vitamin C could be an effective therapy against urinary and sexual distress in participants with rUTI (NCT06268483; ClinicalTrials.gov).

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Sexual dysfunction in female patients of reproductive age group with recurrent urinary tract infection—a cross-sectional study

Cited by 4 publications

References 23 publications

Correlates of Urinary Tract Infections Among Women of Reproductive Age in India: A Systematic Review

Correlates of Urinary Tract Infections Among Women of Reproductive Age in India: A Systematic Review

Recurrent UTI in Women–Risk Factors and Management

Oral preparation of hyaluronic acid, chondroitin sulfate, N-acetylglucosamine, and vitamin C improves sexual and urinary symptoms in participants with recurrent urinary tract infections: a randomized crossover trial

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