Sexual Dysfunction in Male Posttraumatic Stress Disorder Patients

Kotler, Moshe; Cohen, Hagit; Aizenberg, Dov; Matar, Michael A.; Loewenthal, Uri; Kaplan, Zeev; Miodownik, Hanoch; Zemishlany, Zvi

doi:10.1159/000012413

Cited by 91 publications

(105 citation statements)

References 20 publications

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“…It was shown that sexual problems are highly prevalent in psychiatric outpatients, including PTSD patients [1, 2, 3, 4, 5]. Letourneau et al [3] reported that over 80% of PTSD patients studied were experiencing clinically relevant sexual difficulties while erectile dysfunction and premature ejaculation were the most frequently reported problems.…”

Section: Introductionmentioning

confidence: 99%

“…Letourneau et al [3] reported that over 80% of PTSD patients studied were experiencing clinically relevant sexual difficulties while erectile dysfunction and premature ejaculation were the most frequently reported problems. It was suggested that PTSD might be a significant risk factor for sexual problems [3, 4]. …”

Section: Introductionmentioning

confidence: 99%

“…Second, PTSD patients have high rates of comorbid depressive and anxiety disorders that interfere with the maintenance of sexual function in both men and women. Third, the PTSD patients treated with antidepressants demonstrate more impairment in sexual functioning than untreated patients [4]. Furthermore, PTSD patients seem to have long-lasting relation problems with their partners, which may interfere with sexual functioning.…”

Section: Introductionmentioning

confidence: 99%

“…PTSD patients are frequently treated with antidepressants that may contribute to SD [4, 6, 7, 8]. For example, the selective serotonin reuptake inhibitors (SSRIs) may be associated with delayed ejaculation or anorgasmia [9]and can also interfere with sexual desire, arousal and satisfaction [10, 11, 12].…”

Section: Introductionmentioning

confidence: 99%

“…In a recent study, we evaluated the various components of sexual functioning among untreated and SSRI-treated male PTSD patients compared to a group of normal controls [4]. Those treated with SSRIs had greater impairment in desire, arousal and frequency of sexual activity with a partner.…”

Section: Introductionmentioning

confidence: 99%

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Sildenafil Citrate for the Sexual Dysfunction in Antidepressant-Treated Male Patients with Posttraumatic Stress Disorder

Reznik

Zemishlany

Kotler

et al. 2002

Psychother Psychosom

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Background: Previous studies have suggested that posttraumatic stress disorder (PTSD) may be associated with pervasive sexual dysfunction. Sildenafil citrate was established as a highly effective and well-tolerated oral agent for the treatment of sexual dysfunction of various etiologies. There are no studies that have examined the efficacy of oral sildenafil in PTSD patients with sexual dysfunction. Objective: The current study evaluated the impact of sildenafil added to an ongoing antidepressive treatment in male PTSD patients. Methods: Ten consecutive male PTSD patients who complained of sexual dysfunction were enrolled in an open-label 4-week fixed-dose study of sildenafil citrate 50 mg/day p.r.n. Patients were evaluated at baseline and after treatment with the Clinician-Administered PTSD Scale (CAPS); sexual function assessments were performed using the International Index of Erectile Function. Results: All patients completed the study and statistically significant improvement was observed in all evaluated domains of sexual functioning: erectile function (53.5%), orgasmic function (40.3%), sexual desire (53%), intercourse satisfaction (82%) and overall satisfaction (57.4%). Oral sildenafil treatment appeared to be well tolerated and no single patient stopped the treatment. Improvements in various CAPS subscales were also obtained; however, there was no significant correlation between improvement in sexual functioning and the changes in CAPS subscale scores. Conclusion: Sildenafil seems to be an efficacious, safe and well-tolerated treatment of sexual dysfunction in antidepressant-treated male PTSD patients.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Sildenafil Citrate for the Sexual Dysfunction in Antidepressant-Treated Male Patients with Posttraumatic Stress Disorder

Reznik

Zemishlany

Kotler

et al. 2002

Psychother Psychosom

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Demographic and clinical characteristics of motor vehicle accident victims in the community general health outpatient clinic: a comparison of PTSD and non-PTSD subjects

Kupchik¹,

Strous

Erez

et al. 2007

Depress. Anxiety

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Motor vehicle accidents (MVAs) are the leading cause of posttraumatic stress disorder (PTSD) in the general population, often with enduring symptomatology. This study details epidemiological and clinical features that characterize PTSD among MVA victims living in a nonhospitalized community setting long after the MVA event, and includes exploration of premorbid and peritraumatic factors. MVA victims (n=60; 23 males, 37 females) identified from the registry of a community general health outpatient clinic during a 7-year period were administered an extensive structured battery of epidemiological, diagnostic and clinical ratings. Results indicated that 30 subjects (50%; 12 males, 18 females) had MVA-related PTSD (MVAR-PTSD). Among those with PTSD, 16 individuals exhibited PTSD in partial remission, and six, in full remission. There were no significant demographic or occupational function differences between PTSD and non-PTSD groups. The most common comorbid conditions with MVAR-PTSD were social phobia (20%), generalized anxiety disorder (7.8%) and obsessive-compulsive disorder (0.5%). Previous MVA's were not predictive of PTSD. Subjects with MVAR-PTSD scored worse on the Clinician-Administered Posttraumatic Stress Disorder Scale, Part 2 (CAPS-2), Impact of Event Scale, Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, Impulsivity Scale, and Toronto Alexithymia Rating Scale. Study observations indicate a relatively high rate of PTSD following an MVA in a community-based sample. The relatively high rate of partially remitted MVAR-PTSD (N=16) underscores the importance of subsyndromal forms of illness. Alexithymia may be an adaptive method of coping with event stress. The development of PTSD appears not to be associated with the severity of MVA-related physical injury.

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Sexual Behavior and Concerns in a Sample of Elderly, Former Indentured Swiss Child Laborers

2015

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IntroductionPast research suggests a link between post‐traumatic stress disorder (PTSD) and an increased risk for sexual problems. However, there is still no clear picture whether these higher rates are related to trauma exposure or to PTSD itself.AimThe aim of the present study was to complement existing knowledge on the relative impact of trauma and PTSD on sexuality in later life, considering different aspects of trauma exposure on both men and women.MethodsThe study was conducted on a unique population sample of former Swiss indentured child laborers (55 men, M age 78, age range 60–95 years) who have repeatedly experienced a variety of severe childhood traumas.Main Outcome MeasuresSexual outcomes were measured using two scales from the Trauma Symptom Inventory—Dysfunctional Sexual Behavior (DSB) and Sexual Concerns (SC). PTSD symptoms and trauma were assessed with the Short Screening Scale for PTSD and the Composite International Diagnostic Interview, respectively.ResultsTwenty‐two individuals showed PTSD symptoms, and 53 reported having experienced childhood trauma. Significant differences between men and women were reported for DSB and SC. Men reported a significantly higher prevalence of both SC and DSB compared with women.ConclusionsThis is the very first study investigating DSB and SC in a sample of older adults exposed to similar traumatic experiences and settings. However, some study limitations need to be considered such as the small sample size. Additional studies are needed to further explore the relative role of traumatization and PTSD on sexual behavior and well‐being, especially to improve sexual therapy for patients who experience trauma. Rechsteiner K, Burri A, and Maercker A. Sexual behavior and concerns in a sample of elderly, former indentured Swiss child laborers. Sex Med 2015;3:305–314.

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Sexual Dysfunction in Male Posttraumatic Stress Disorder Patients

Cited by 91 publications

References 20 publications

Sildenafil Citrate for the Sexual Dysfunction in Antidepressant-Treated Male Patients with Posttraumatic Stress Disorder

Sildenafil Citrate for the Sexual Dysfunction in Antidepressant-Treated Male Patients with Posttraumatic Stress Disorder

Demographic and clinical characteristics of motor vehicle accident victims in the community general health outpatient clinic: a comparison of PTSD and non-PTSD subjects

Sexual Behavior and Concerns in a Sample of Elderly, Former Indentured Swiss Child Laborers

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