Sexual dysfunctions in HCV patients and its correlations with psychological and biological variables

Soykan, Atilla; Boztaş, Hamid; Idilman, R.; Ozel, Ezgi; Tüzün, Ali; Özden, Ali; Kumbasar, Hakan

doi:10.1038/sj.ijir.3901267

Cited by 40 publications

(46 citation statements)

References 14 publications

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“…22 Soykan et al reported that sexual dysfunction was in (21%) of the cases with chronic HCV. 15 Further more Danoff et al and Foster reported in accordance with our results strong association between sexual dysfunction and advanced hepatic fibrosis or cirrhosis. 23,24 HBV positive patients 11.8% reported sexual dysfunction, remaining had HBV+HCV positive 2.9%, HBV+HDV positive 1.5%.…”

Section: Discussionsupporting

confidence: 81%

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Sexual Dysfunction; Patients With Chronic Liver Disease

Bawany

Sahito²,

Naz³

et al. 2017

TPMJ

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ABSTRACT… Objectives:To determine the frequency of sexual dysfunction in the patients suffering from chronic liver disease. Period: 1 year from June 2013 to May 2014. Study Design: An observational study. Setting: Asian Institute of Medical Sciences. Methodology: 150 cases of chronic liver disease including patients of both genders at Asian Institute of medical sciences who had suggestive history and signs /symptoms of sexual dysfunction. Results: Study found 51.3% of total patients were suffering with sexual dysfunction. Out of all participating females, 52.2% were affected and among the total male patients 51% males were suffering from sexual dysfunction. Hepatitis C virus (HCV) and Hepatitis B virus (HBV) were positive in 76.7% and 11.3%, respectively. Conclusion: Sexual dysfunction is a common complication in the patients suffering from chronic liver disease.

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Section: Discussionsupporting

confidence: 81%

“…15,16 In a study conducted by Nolte et al reported that in seventeen male patients, those who underwent (transjugular intrahepatic port systemic stent shunting), 30% -70% erectile dysfunction increased. 17 In another study by James H et al also showed partial sexual dysfunction in the 20.6% and complete dysfunction in the 34.3% of the cases.…”

Section: Discussionmentioning

confidence: 99%

Sexual Dysfunction; Patients With Chronic Liver Disease

Bawany

Sahito²,

Naz³

et al. 2017

TPMJ

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“…Few studies have systematically investigated SD in women with CHC. Soykan et al performed a cross-sectional study of 46 IFN-α-naive CHC patients and found higher rates of SD in women (50%) than in men (21%) 14 . More recently, Elshimi et al evaluated SD in women with CHC before IFN-α treatment and in controls 15 .…”

Section: Introductionmentioning

confidence: 99%

Sexual dysfunction and dissatisfaction in chronic hepatitis C patients

Fábregas

Moura

Ávila

et al. 2014

Rev. Soc. Bras. Med. Trop.

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564www.scielo.br/rsbmt I www.rsbmt.org.br Revista da Sociedade Brasileira de Medicina Tropical 47(5):564-572, Sep-Oct, 2014http://dx.doi. org/10.1590/0037-8682-0147-2014 Major Article ABSTRACT Introduction: The prevalence of sexual dysfunction (SD) and dissatisfaction with sexual life (DSL) in patients with chronic hepatitis C virus infection (CHC) was jointly investigated via a thorough psychopathological analysis, which included dimensions such as fatigue, impulsiveness, psychiatric comorbidity, health-related quality of life (HRQL) and sociodemographic and clinical characteristics. Methods: Male and female CHC patients from an outpatient referral center were assessed using the Brief Fatigue Inventory, the Barrat Impulsiveness Scale, the Beck Depression Inventory (BDI), the Hospital Anxiety and Depression Scale, the Hamilton Anxiety Scale (HAM-A), and the World Health Organization Quality of Life Scale-Brief Version (WHOQOL-BREF). Structured psychiatric interviews were performed according to the Mini-International Neuropsychiatric Interview. SD was assessed based on specifi c items in the BDI (item 21) and the HAM-A (item 12). DSL was assessed based on a specifi c question in the WHOQOL-BREF (item 21). Multivariate analysis was performed according to an ordinal linear regression model in which SD and DSL were considered as outcome variables. Results: SD was reported by 60 (57.1%) of the patients according to the results of the BDI and by 54 (51.4%) of the patients according to the results of the HAM-A. SD was associated with older age, female gender, viral genotype 2 or 3, interferon-α use, impulsiveness, depressive symptoms, antidepressant and benzodiazepine use, and lower HRQL. DSL was reported by 34 (32.4%) of the patients and was associated with depressive symptoms, anxiety symptoms, antidepressant use, and lower HRQL. Conclusions: The prevalence of SD and DSL in CHC patients was high and was associated with factors, such as depressive symptoms and antidepressant use. Screening and managing these conditions represent signifi cant steps toward improving medical assistance and the HRQL of CHC patients.

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“…Finally, our symptom measure did not ask about sexual symptoms related to HIV or HCV infection, and no participant discussed sexual symptoms in response to open-ended interview questions. However, recent data and clinical experience indicate that sexual functioning and symptoms (e.g., impotence) may be related to HCV infection (Ferri, Bertozzi, & Zignego, 2002;Soykan et al, 2005). Future studies will need to include specific measures of sexual symptoms in studies of adults with HIV/HCV co-infection.…”

Section: Limitationsmentioning

confidence: 99%