Sexual function and quality of life in gynecological cancer pre- and post-short-term brachytherapy: a prospective study

Zomkowski, Kamilla; Toryi, Ariana Machado; Sacomori, Cinara; Dias, Mirella; Sperandio, Fabiana Flores

doi:10.1007/s00404-016-4099-5

Cited by 9 publications

(6 citation statements)

References 35 publications

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“…FSD can occur due to several anatomical conditions such as genital mutilation; pathological conditions such as endometriosis, gynecological cancer, urinary infections, urinary incontinence, endocrine alterations, and degenerative and vascular diseases; and also by psychological problems such as depression and the use of psychoactive drugs [4,5].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of female sexual dysfunction in Brazil: A systematic review

Wolpe

Zomkowski

Silva

et al. 2017

European Journal of Obstetrics & Gynecology and Reproductiv

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The aim of this systematic review is to investigate the prevalence of female sexual dysfunction in the Brazilian population. This is a systematic review conducted in July 2016 in which four databases were searched: MEDLINE/Pubmed, Scopus, LILACS, and Cinahl. Two investigators extracted the primary data, which were fully analyzed, and applied the inclusion/exclusion criteria. The search found 113 results, and 20 of them compounded the scope of this study. Only four of the studies showed good methodology quality. The main diagnostics criteria used were validated questionnaires specific for sexual function assessment. Regarding the variation of prevalence values, female sexual dysfunction ranged from 13.3% to 79.3% of the studied population, while this value for changes in sexual desire ranged from 11% to 75%, arousal from 8% to 68.2%, lubrication from 29.1% to 41.4%, orgasm from 18% to 55.4%, and satisfaction from 3.3% to 42%; sexual activity frequency ranged from 55.8% to 78.5%, dyspareunia from 1.2% to 56.1%, and pleasure modifications was not addressed. Beside the divergences among studies, there is still a high prevalence of female sexual dysfunction in Brazil.

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Section: Introductionmentioning

confidence: 99%

Prevalence of female sexual dysfunction in Brazil: A systematic review

Wolpe

Zomkowski

Silva

et al. 2017

European Journal of Obstetrics & Gynecology and Reproductiv

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“…In 40%-60% of women being treated for gynecological cancer, interest in sex, sexual desire and frequency of relations have been found to diminish [24], while 43.4% of women do not feel as much sexual desire as before the illness [13]. It is known that radiotherapy causes a shortening and stenosis of the vagina [25] and vaginal dryness [18,26]. The shortening of the vaginal canal, vaginal dryness and stenosis can cause dyspareunia and result in a woman's aversion to sex and a diminishing of the frequency of sexual intercourse [18,26].…”

Section: Discussionmentioning

confidence: 99%

“…It is known that radiotherapy causes a shortening and stenosis of the vagina [25] and vaginal dryness [18,26]. The shortening of the vaginal canal, vaginal dryness and stenosis can cause dyspareunia and result in a woman's aversion to sex and a diminishing of the frequency of sexual intercourse [18,26]. Among individuals who are sexually active, have a diagnosis of endometrial cancer, and receive intravaginal high-dose rate brachytherapy, 32% have been found to suffer from dyspareunia and 27% from vaginal dryness and vaginal discharge [27].…”

Section: Discussionmentioning

confidence: 99%

Brakiterapi Alan Serviks ve Endometium Kanserli Hastalarda Cinsel İşlevsellik ve Etkileyen Faktörler

Özmen¹,

Mert²

2020

Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi

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Bu araştırmanın amacı, brakiterapi alan serviks ve endometium kanserli hastalarda cinsel fonksiyonunu değerlendirmek ve cinsel fonksiyonu etkileyen faktörleri incelemektir. Gereç ve Yöntemler: Araştırma, katitatif ve kantitatif araştırma tekniğinin kullanıldığı bir çalışmadır. Bu araştırmaya bir Üniversite Uygulama ve Araştırma Hastanesi'nin Radyasyon Onkoloji Ünitesi'nde 26.10.2018-01.03.2019 tarihleri arasında serviks ve endometrium kanseri nedeniyle brakiterapi alan ve araştırma kritelerine uygun yirmi bir hasta ile yürütülmüştür. Bulgular: Katılımcıların Kadın Cinsel İşlev Ölçeği (FSFI) puan ortalaması 19.28±22.72 olup, %66,7'sinde cinsel işlev bozukluğu olduğu belirlenmiştir. Cinsel fonksiyonu etkileyen faktörler; hastalığa verilen tepki, cinsellik ve eşlerin yaklaşımı olmak üzere üç ana tema altında incelenmiştir. Hastalığa verilen tepki temasının altında üzüntü, çaresizlik, hastalığı kabullenme alt temaları; cinsellik ana temasında; cinsel isteksizlik, cinsel ilişkiyi red etme alt temaları; eşlerin yaklaşımı ana temasında ise; hoşgörü ve anal seks alt temaları belirlenmiştir. Sonuç: Brakiterapi alan servikal ve endometrium kanserli hastalar cinsel fonksiyon bozukluğu yaşamakta ve buna yönelik danışmanlık hizmeti alamamaktadır.

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“…Radiotherapy involves two techniques of application, an external and intracavitary way, and has been considered fundamental to the increase in rates of recurrence-free survival [8–10]. However, the use of ionizing radiation induces difficult-to-resolve adverse effects that may adversely interfere with treatment [11].…”

Section: Introductionmentioning

confidence: 99%

Clinical and Psychological Outcomes of the Use of Vaginal Dilators After Gynaecological Brachytherapy: a Randomized Clinical Trial

et al. 2019

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IntroductionThe aim of this study was to evaluate the dimensions of the vaginal canal in patients undergoing gynaecological brachytherapy and the effect of the use of vaginal dilators (VD) used in the follow-up of pelvic physiotherapy.MethodsA total of 88 patients were randomly allocated to the control group (CG) and intervention group (IG). Three evaluations were performed: pre-brachytherapy, post-brachytherapy and follow-up of 3 months. The CG received standard guidance from the health team while the IG was instructed to use VD for 3 months. The dimensions of the vaginal canal (main outcome) were defined by the length of the vagina (centimetres), width (number of full clockwise turns of the opening thread of a gynaecological speculum) and area (defined by the size of the VD). Quality of life and pelvic floor (PF) functionality were also evaluated.ResultsThere was no effect of the VD on vaginal length, width and area among the intention-to-treat (ITT) population. However, in the analysis stratified by adhesion, the CG had a significant decrease in the vaginal area. PF was predominantly hypoactive throughout the follow-up. Quality of life improved in both groups, but the reduction of constipation, vaginal dryness and stress urinary incontinence manifested only in the IG.ConclusionThe use of VD did not alter the dimensions of the vaginal canal within the first 3 months after the end of radiotherapy treatment. However, there was a large sample loss during follow-up so studies with a larger sample number and longer follow-up time need to be conducted.Trial RegistrationClinicalTrials.gov Identifier NCT03090217.Electronic Supplementary MaterialThe online version of this article (10.1007/s12325-019-01006-4) contains supplementary material, which is available to authorized users.

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Sexual function and quality of life in gynecological cancer pre- and post-short-term brachytherapy: a prospective study

Abstract: There was a worsening of quality of life in comparing pre- and post-evaluations related to gastrointestinal symptoms over a period equivalent to 40 days. Regarding sexual function, lack of lubrication was identified in short-term post-gynecological cancer brachytherapy.

Cited by 9 publications

References 35 publications

Prevalence of female sexual dysfunction in Brazil: A systematic review

Prevalence of female sexual dysfunction in Brazil: A systematic review

Brakiterapi Alan Serviks ve Endometium Kanserli Hastalarda Cinsel İşlevsellik ve Etkileyen Faktörler

Clinical and Psychological Outcomes of the Use of Vaginal Dilators After Gynaecological Brachytherapy: a Randomized Clinical Trial

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