Sexual Functions, Sexual Organs and Sex Hormone Level in Chronic Alcohol Intake

Aluko, Esther Oluwasola; Olubobokun, T. H.; Adekunbi, Daniel; Nna, Victor Udo

doi:10.9734/bjmmr/2014/7035

Cited by 4 publications

(1 citation statement)

References 75 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ethanol intoxication affects the hormonal levels of estrogen and progesterone, which leads to hyperprolactinemia (Olusola et al 2014). Previously, it has been suggested that the optimal blood level of FSH is known to be a prerequisite for initiation and maintenance of normal ovarian folliculogenesis (Monfared and Salati 2013).…”

Section: Discussionmentioning

confidence: 99%

Amelioration of ethanol intoxicated ovarian dysfunction by Alocasia indica tuber: possible involvement of nuclear factor kappa B

Pal,

Bhattacharjee,

Banerjee

et al. 2021

EEB

View full text Add to dashboard Cite

The protective efficacy of ethanolic extract of Alocasia indica tuber was studied on ethanol-intoxicated ovaries of rats, searching for the possible involvement of expression levels of nuclear factor kappa B (NF-κB) and caspase-3. The extract was prepared by 80% ethanol using Soxhlet. Female albino rats were intraperitoneally injected by ethanol (3 g kg -1 body weight per day) with and without extract (200 and 400 mg kg -1 body weight per day) for a period of 14 days. Oxidative stress parameters and the gonadal hormone profile were determined, and apoptosis assay and immuno-staining of NF-κB and caspase-3 were conducted. Oxidative stress parameters and antioxidant enzyme levels were regained by 41 to 90% and 36 to 96%, respectively, by extract at a higher dose in ethanol intoxicated rat. Decreased levels (18 to 28%) of follicle stimulating hormone, luteinizing hormone, estrogen and progesterone level due to ethanol intoxication were restored (19 to 98%) by extract at same dose, whereas elevated level of prolactin and corticosterone level were restored by 51 to 81%. The extract reduced number of apoptotic dead cells in the ovary with altered expression of NF-κB and caspase-3, indicated by lower number of positively stained cells in extract-treated rats. It appears that ethanolic extract of A. indica can suppress ethanolinduced ovarian apoptotic cell death and other reproductive changes.

show abstract

Section: Discussionmentioning

confidence: 99%

Amelioration of ethanol intoxicated ovarian dysfunction by Alocasia indica tuber: possible involvement of nuclear factor kappa B

Pal,

Bhattacharjee,

Banerjee

et al. 2021

EEB

View full text Add to dashboard Cite

show abstract

Alcoholic beer consumption permutes P21 and cyclin D1 expression, oxidative stress factors, and histomorphometric parameters in rat testis

Zamir-Nasta,

Abbasi,

Amini

et al. 2024

Alcohol

View full text Add to dashboard Cite

Alcohol Use and Sexual Functioning: A Study of Adult Males in Primary Care

Esangbedo,

Okonkwo,

Ajayi

et al. 2024

Preprint

View full text Add to dashboard Cite

This study examined the prevalence, risk factors, and healthcare implications associated with alcohol use and sexual functioning among adult male primary care patients. The study focused on a sample of over 2,100 men and utilized comprehensive assessments of sexual functioning and alcohol use to assess the associations in a variety of domains. It adopted a Cross-Sectional approach involving sexually active adult males from 18–40 years old in a relationship, who drink alcohol at least twice per week. Study instruments used include the Proforma, IIEF, AUDIT etc. It used the finite population correction factor statistic to determine the right sample size, taking into account the size of the population which resulted in a more accurate estimate of the population parameter of interest. Analysis was carried out with statistical package for social sciences (SPSS) at a 95% confidence interval. From the study results, a considerable number of male participants, approximately 25%, were found to have alcohol use disorders, and 44.2% of them reported experiencing sexual dysfunctions. Furthermore, the research findings suggested that advancing age was associated with an increased risk of problematic alcohol use, whereas lower income was linked to a higher likelihood of sexual dysfunction. Most significantly, the research found a connection between sexual dysfunction and the consumption of alcohol. Individuals who consumed alcohol excessively had notably reduced sexual functioning overall, including impaired erectile and ejaculatory function, as well as a decreased sexual desire. This highlights the need for comprehensive assessment and targeted interventions to improve the health of men in primary care, which should include alcohol use screenings and interventions as well as sexual health care. The implications of this study are that men who consume alcohol are exposed to increased risks of impaired sexual functioning. As such, primary care providers should be aware of the risks and consider the implementation of alcohol use assessments and appropriate interventions to improve their patient’s health outcomes. Additionally, educational programs should be implemented in order to increase awareness of the risks associated with alcohol use and sexual functioning among men in primary care.

show abstract

Sexual Functions, Sexual Organs and Sex Hormone Level in Chronic Alcohol Intake

Cited by 4 publications

References 75 publications

Amelioration of ethanol intoxicated ovarian dysfunction by Alocasia indica tuber: possible involvement of nuclear factor kappa B

Amelioration of ethanol intoxicated ovarian dysfunction by Alocasia indica tuber: possible involvement of nuclear factor kappa B

Alcoholic beer consumption permutes P21 and cyclin D1 expression, oxidative stress factors, and histomorphometric parameters in rat testis

Alcohol Use and Sexual Functioning: A Study of Adult Males in Primary Care

Contact Info

Product

Resources

About