Sexual life impact evaluation of different hormonal contraceptives on the basis of their methods of administration

Guida, Maurizio; Cibarelli, Francesca; Troisi, Jacopo; Gallo, Alessandra; Palumbo, A.; Sardo, Attilio Di Spiezio

doi:10.1007/s00404-014-3323-4

Cited by 25 publications

(21 citation statements)

References 22 publications

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“…In a comparison between the vaginal ring, an oral CHC containing a third-generation progestin, subdermal contraception, and no hormonal contraception (control group), the three groups using an HC had increased positive indicators of sexual function (sexual interest and fantasies, orgasm number and intensity, and satisfaction) and decreased negative indicators (anxiety and discomfort). The same results were obtained in a comparison between etonogestrel implant and no contraception [2,52]. LNG-IUS have also been positively associated with sexual desire, arousal, orgasm, and overall sexual function compared with no contraception [2,53].…”

Section: Resultssupporting

confidence: 62%

Hormonal Contraceptives, Female Sexual Dysfunction, and Managing Strategies: A Review

Casado‐Espada

Alarcón

Iglesia-Larrad

et al. 2019

JCM

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In recent decades, hormonal contraceptives (HC) has made a difference in the control of female fertility, taking an unequivocal role in improving contraceptive efficacy. Some side effects of hormonal treatments have been carefully studied. However, the influence of these drugs on female sexual functioning is not so clear, although variations in the plasma levels of sexual hormones could be associated with sexual dysfunction. Permanent hormonal modifications, during menopause or caused by some endocrine pathologies, could be directly related to sexual dysfunction in some cases but not in all of them. HC use seems to be responsible for a decrease of circulating androgen, estradiol, and progesterone levels, as well as for the inhibition of oxytocin functioning. Hormonal contraceptive use could alter women’s pair-bonding behavior, reduce neural response to the expectation of erotic stimuli, and increase sexual jealousy. There are contradictory results from different studies regarding the association between sexual dysfunction and hormonal contraceptives, so it could be firmly said that additional research is needed. When contraceptive-related female sexual dysfunction is suspected, the recommended therapy is the discontinuation of contraceptives with consideration of an alternative method, such as levonorgestrel-releasing intrauterine systems, copper intrauterine contraceptives, etonogestrel implants, the permanent sterilization of either partner (when future fertility is not desired), or a contraceptive ring.

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Section: Resultssupporting

confidence: 62%

Hormonal Contraceptives, Female Sexual Dysfunction, and Managing Strategies: A Review

Casado‐Espada

Alarcón

Iglesia-Larrad

et al. 2019

JCM

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“…Moreover, when the implant was compared to other types of contraceptives women who used the subcutaneous implant had higher scores on the McCoy female sexuality questionnaire and higher levels of androstenedione [9, 13].…”

Section: Discussionmentioning

confidence: 99%

“…Influence of hormonal contraceptives on sexual life is not frequently reported. Data published to date are contrasting and refer to the combined short-acting hormonal oral [3, 4] and vaginal contraceptives [5, 6], while studies on the influence of subdermal contraception are few, and not specifically focused on female sexual function [7–9].…”

Section: Introductionmentioning

confidence: 99%

Nexplanon Subdermal Implant: Assessment of Sexual Profile, Metabolism, and Bleeding in a Cohort of Italian Women

Guida

Farris

Aquino

et al. 2019

BioMed Research International

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Objectives. To evaluate the impact on metabolism, bleeding, and sexual function of Nexplanon, a subdermal implant. Study Design. We recruited women (n=101) receiving the Nexplanon implant at two university centers in Italy between 2011 and 2016 into this prospective, observational, multicenter research trial. Participants completed the Interview for Ratings of Sexual Function (IRSF) and the Female Sexual Function Index (FSFI) questionnaires before and 3 and 6 months after the implant was inserted. In addition, all blood parameters were assessed at these visits. All women were given a menstrual diary card and a pictorial blood assessment chart to record daily any vaginal bleeding. Results. The studied metabolic parameters remained in the normal range, showing no alarming modifications: minimal statistical reductions (in aspartate aminotransferase, alanine aminotransferase, total cholesterol, triglycerides, and activated partial thromboplastin time) and increases (in glucose and prothrombin activity) were observed. Changes in IRSF score over 6 months showed a significant increase in pleasure, personal initiative, orgasm, intensity of orgasm, and satisfaction, and a significant decrease in anxiety and discomfort. Mean Body Mass Index decreased, and the weekly frequency of sexual intercourse increased. Conclusions. Nexplanon showed not only a lower metabolic and bleeding impact, but also important positive effects on sexual function. It expands the range of possibilities for women, 38 and couples, in the modern concepts of sexual and reproductive wellbeing.

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“…Compared to women using the ring, pill, or no method (control group), after 6 months, implant users reported the most significant improvements in sexual discomfort, anxiousness, personal initiative, and fantasy. All method users reported significantly more sexual pleasure, satisfaction and higher orgasm frequency at 6 months compared to controls (Guida et al, 2014) Women reported that the ring was more likely to interfere with sex compared to the pill and significantly more women reported that their sex partners preferred the pill (Stewart et al, 2007).…”

Section: "Multiplementioning

confidence: 92%

The Sexual Acceptability of Contraception: Reviewing the Literature and Building a New Concept

Higgins

Smith

2016

The Journal of Sex Research

175

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How contraceptives affect women’s sexual well-being is critically understudied. Fortunately, a growing literature focuses on sexual aspects of contraception, especially hormonal contraception’s associations with libido. However, a more holistic approach to contraceptive sexual acceptability is needed to capture the full range of women’s sexual experiences. We conducted a narrative literature review of this topic, working with an original sample of 3,001 citations published from 2005 to 2015. In Part 1, we draw from a subset of this literature (264 citations) to build a new conceptual model of sexual acceptability. Aspects include macro factors (gender, social inequality, culture, and structure), relationship factors (dyadic influences and partner preferences), and individual factors (sexual functioning, sexual preferences, such as dis/inhibition, spontaneity, pleasure, the sexual aspects of side effects, such as bleeding, mood changes, sexual identity and sexual minority status, and pregnancy intentions). In Part 2, we review the empirical literature on the sexual acceptability of individual methods (103 citations), applying the model as much as possible. Results suggest contraceptives can affect women’s sexuality in a wide variety of positive and negative ways that extend beyond sexual functioning alone. More attention to sexual acceptability could promote both women’s sexual well-being and more widespread, user-friendly contraceptive practices.

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Sexual life impact evaluation of different hormonal contraceptives on the basis of their methods of administration

Abstract: Subdermal contraception is slower than both intravaginal and oral hormonal contraceptives in giving these effects, but is more effective after a cycle of 6 months of usage.

Cited by 25 publications

References 22 publications

Hormonal Contraceptives, Female Sexual Dysfunction, and Managing Strategies: A Review

Hormonal Contraceptives, Female Sexual Dysfunction, and Managing Strategies: A Review

Nexplanon Subdermal Implant: Assessment of Sexual Profile, Metabolism, and Bleeding in a Cohort of Italian Women

The Sexual Acceptability of Contraception: Reviewing the Literature and Building a New Concept

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