Sexual maturity, molting, and reproductive activity in the Carib Grackle (Quiscalus lugubris)

Saavedra, Luisa F.; Figueroa, Yadi X.; Serrano-Cardozo, Víctor H.; Ramírez‐Pinilla, Martha Patricia

doi:10.1007/s43388-021-00070-1

Cited by 1 publication

(1 citation statement)

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“…Exploring the occurrence, processes, and judgment criteria of animal sexual maturity has important scientific and economic value for understanding physiological changes in species and guiding their reproduction. Various studies on sexual maturation have been conducted across a wide range of species, such as RM [ 2 ], Atlantic salmon ( Salmo salar ) [ 3 ], Atlantic bluefin tuna ( Thunnus thynnus ) [ 4 ], Carib grackle ( Quiscalus lugubris ) [ 5 ], macaroni penguin ( Eudyptes chrysolophus ) [ 6 ], northern fur seal ( Callorhinus ursinus ) [ 7 ], and wild boar ( Sus scrofa ) [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Multi-omics analysis reveals changes in tryptophan and cholesterol metabolism before and after sexual maturation in captive macaques

Liu

Wang

et al. 2023

BMC Genomics

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Rhesus macaques (Macaca mulatta, RMs) are widely used in sexual maturation studies due to their high genetic and physiological similarity to humans. However, judging sexual maturity in captive RMs based on blood physiological indicators, female menstruation, and male ejaculation behavior can be inaccurate. Here, we explored changes in RMs before and after sexual maturation based on multi-omics analysis and identified markers for determining sexual maturity. We found that differentially expressed microbiota, metabolites, and genes before and after sexual maturation showed many potential correlations. Specifically, genes involved in spermatogenesis (TSSK2, HSP90AA1, SOX5, SPAG16, and SPATC1) were up-regulated in male macaques, and significant changes in gene (CD36), metabolites (cholesterol, 7-ketolithocholic acid, and 12-ketolithocholic acid), and microbiota (Lactobacillus) related to cholesterol metabolism were also found, suggesting the sexually mature males have stronger sperm fertility and cholesterol metabolism compared to sexually immature males. In female macaques, most differences before and after sexual maturity were related to tryptophan metabolism, including changes in IDO1, IDO2, IFNGR2, IL1Β, IL10, L-tryptophan, kynurenic acid (KA), indole-3-acetic acid (IAA), indoleacetaldehyde, and Bifidobacteria, indicating that sexually mature females exhibit stronger neuromodulation and intestinal immunity than sexually immature females. Cholesterol metabolism-related changes (CD36, 7-ketolithocholic acid, 12-ketolithocholic acid) were also observed in female and male macaques. Exploring differences before and after sexual maturation through multi-omics, we identified potential biomarkers of sexual maturity in RMs, including Lactobacillus (for males) and Bifidobacterium (for females) valuable for RM breeding and sexual maturation research.

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