Sexual Network Patterns and Their Association With Genital and Anal Human Papillomavirus Infection in Adolescent and Young Men

Partner-Level and Sexual Networking Factors Are Associated With Vaccine-Type and Nonvaccine-Type Human Papillomavirus Infection After Vaccine Introduction in Young Women

“…15 Finally, in a study of 13-to 26-year-old young men in the United States, partner concurrency was associated with HPV-16/18 detection in unvaccinated and vaccinated men. 16 Our findings imply that young women whose partners practice concurrency are at elevated risk for HPV in the post-HPV-vaccination era and should be targeted for education about cervical cancer prevention through safer sexual behaviors, vaccination (if unvaccinated), and cervical cancer screening when indicated. However, partner-level and sexual networking behaviors are not routinely assessed in the sexual history and should be considered by clinicians as a component of routine care given their consistent association with HPV and other STIs.…”

“…In a study of adult Taiwanese men who have sex with men, concurrency was associated with penile HPV detection 15 . Finally, in a study of 13- to 26-year-old young men in the United States, partner concurrency was associated with HPV-16/18 detection in unvaccinated and vaccinated men 16 . Our findings imply that young women whose partners practice concurrency are at elevated risk for HPV in the post–HPV-vaccination era and should be targeted for education about cervical cancer prevention through safer sexual behaviors, vaccination (if unvaccinated), and cervical cancer screening when indicated.…”

“…Discordance may be a marker for engaging in riskier sexual behaviors; for example, if it leads to a limited ability to negotiate condom use, and concurrency increases the risk of STI transmission. Discordance and concurrency have been shown to be associated with bacterial STIs and HIV, 10–12 but few studies have explored associations with HPV, and those studies were largely conducted in adult populations 13–17 . Furthermore, data are needed regarding whether risk factors for HPV are different after HPV vaccines were introduced, whether factors associated with HPV differ for vaccine-type and non–vaccine-type HPV, and whether any associations vary by vaccination status.…”

“…The aim of this study was to determine individual-level, partner-level, and sexual networking factors associated with vaccine-type and non–vaccine-type HPV in vaccinated and unvaccinated young women. Based on the results of a recent study we conducted among adolescent and young adult men, 16 we hypothesized that partner-level and sexual networking factors would be associated with both vaccine-type and non–vaccine-type HPV in vaccinated and unvaccinated young women.…”

Health inequities in human papillomavirus prevention, diagnostics and clinical care in the USA: a scoping review

“…Except for Hispanic patients, historically marginalised racial/ethnic groups had disproportionately lower rates of vaccination and decreased knowledge of HPV (online supplemental table 2). Additionally, these populations had lower physician recommendation for vaccination,20–22 higher prevalence of HPV infections23–32 and were less likely to undergo primary surgery as treatment for HPV-associated cancer 33–35. Although vaccination rates among Hispanic patients were relatively high, all historically marginalised racial/ethnic populations had higher rates of HPV-associated cancer36 and worse cancer-related outcomes compared with white patients 37…”