“…Germane to the present study of these youth, previous analyses have revealed differential effects of mental health problems (Dembo, Wareham, Schmeidler, Briones-Robinson, & Winters, 2014), substantial co-morbidity of problem behaviors among the youth (Dembo, Briones-Robinson, et al, 2012; Dembo, Wareham, Schmeidler, & Winters, in press), and trends in sexual risk behaviors over time for the total sample that are associated with trends in substance use over time (Dembo, Briones-Robinson, Barrett, et al, 2014; Dembo, Briones-Robinson, Ungaro et al, 2014; Dembo, Briones-Robinson, Wareham, et al, 2016). More recently, latent class analyses revealed gender differences in the association between sexual risk behaviors and depression symptoms (Dembo, Wareham, Krupa, & Winters, in press). To date, however, none of the analyses using this sample have examined the simultaneous association between marijuana use, depression symptoms, and sexual risk behaviors on sexual risk over time and gender differences.…”