SEXUAL SELECTION ACCELERATES THE ELIMINATION OF A DELETERIOUS MUTANT IN<i>DROSOPHILA MELANOGASTER</i>

Hollis, Brian; Fierst, Janna L.; Houle, David

doi:10.1111/j.1558-5646.2008.00551.x

Cited by 84 publications

(93 citation statements)

References 71 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This has been applied for a handful of deleterious alleles [34,35], revealing effects that vary among mutations. Given such variability, obtaining a general picture of the genome-wide consequences of sexual selection for adaptation via a single-mutation approach will be difficult.…”

Section: Resultsmentioning

confidence: 99%

Genomic Evidence that Sexual Selection Impedes Adaptation to a Novel Environment

et al. 2015

View full text Add to dashboard Cite

Sexual selection is widely appreciated for generating remarkable phenotypic diversity, but its contribution to adaptation and the purging of deleterious mutations is unresolved. To provide insight into the impact of sexual selection on naturally segregating polymorphisms across the genome, we previously evolved 12 populations of Drosophila serrata in a novel environment employing a factorial manipulation of the opportunities for natural and sexual selection. Here, we genotype more than 1,400 SNPs in the evolved populations and reveal that sexual selection affected many of the same genomic regions as natural selection, aligning with it as often as opposing it. Intriguingly, more than half of the 80 SNPs showing treatment effects revealed an interaction between natural and sexual selection. For these SNPs, while sexual selection alone often caused a change in allele frequency in the same direction as natural selection alone, when natural and sexual selection occurred together, changes in allele frequency were greatly reduced or even reversed. This suggests an antagonism between natural and sexual selection arising from male-induced harm to females. Behavioral experiments showed that males preferentially courted and mated with high-fitness females, and that the harm associated with this increased male attention eliminated the female fitness advantage. During our experiment, females carrying otherwise adaptive alleles may therefore have disproportionally suffered male-induced harm due to their increased sexual attractiveness. These results suggest that a class of otherwise adaptive mutations may not contribute to adaptation when mating systems involve sexual conflict and male mate preferences.

show abstract

Section: Resultsmentioning

confidence: 99%

Genomic Evidence that Sexual Selection Impedes Adaptation to a Novel Environment

et al. 2015

View full text Add to dashboard Cite

show abstract

“…They imply that sexual selection on males combined with constraints on sexually dimorphic gene expression limit the evolution of transcriptomes optimized for female performance, the primary determinant of a population's reproductive output in species without paternal care. Thus, although sexual selection may facilitate adaptation by promoting good genes 28 , it appears to simultaneously impose a load on populations that negatively affects ecological success.…”

Section: Nature Communications | Doi: 101038/ncomms4482mentioning

confidence: 99%

Evolution under monogamy feminizes gene expression in Drosophila melanogaster

et al. 2014

Self Cite

View full text Add to dashboard Cite

Many genes have evolved sexually dimorphic expression as a consequence of divergent selection on males and females. However, because the sexes share a genome, the extent to which evolution can shape gene expression independently in each sex is controversial. Here, we use experimental evolution to reveal suboptimal sex-specific expression for much of the genome. By enforcing a monogamous mating system in populations of Drosophila melanogaster for over 100 generations, we eliminated major components of selection on males: female choice and male-male competition. If gene expression is subject to sexually antagonistic selection, relaxed selection on males should cause evolution towards female optima. Monogamous males and females show this pattern of feminization in both the whole-body and head transcriptomes. Genes with male-biased expression patterns evolved decreased expression under monogamy, while genes with female-biased expression evolved increased expression, relative to polygamous populations. Our results demonstrate persistent and widespread evolutionary tension between male and female adaptation.

show abstract

“…Interestingly, some empirical evidence suggests that good genes sexual selection via mate choice is in fact effective at purging harmful mutations (Hollis, Fierst, & Houle, 2009), as well as increasing mean species fitness and facilitating adaptation to an environment (Lorch, Proulx, Rowe, & Day, 2003;Fricke & Arnqvist, 2007).…”

mentioning

confidence: 99%

Cognitive Traits as Sexually Selected Fitness Indicators

Klasios

2013

Review of General Psychology

View full text Add to dashboard Cite

The evolutionary psychologist Geoffrey Miller has argued that various features of human psychology have been sculpted, at least in part, by the evolutionary process of sexual selection via mate choice. This paper specifically examines the central claim of Miller's account, namely that certain cognitive traits have evolved to function as good genes fitness indicators. First, Iexpound on and clarify key foundational concepts comprising the focal hypothesis, especially condition-dependence, mutation target size, and mutation-selection balance. Second, I proceed to highlight some subtle distinctions with respect to the concepts of exaptation and adaptation, as well as Fisherian runaway selection and good genes sexual selection, all of which in turn bear importantly on the overall framework of cognitive traits as fitness indicators. Third and finally, Iclose out the paper by examining various conceptual and methodological criteria which are integral to identifying sexually-selected adaptations, then briefly examine some empirical work that has aimed to test the hypotheses that traits such as humor and creativity function as sexually attractive fitness indicators.

show abstract

SEXUAL SELECTION ACCELERATES THE ELIMINATION OF A DELETERIOUS MUTANT INDROSOPHILA MELANOGASTER

Cited by 84 publications

References 71 publications

Genomic Evidence that Sexual Selection Impedes Adaptation to a Novel Environment

Genomic Evidence that Sexual Selection Impedes Adaptation to a Novel Environment

Evolution under monogamy feminizes gene expression in Drosophila melanogaster

Cognitive Traits as Sexually Selected Fitness Indicators

Contact Info

Product

Resources

About