2019
DOI: 10.1080/13697137.2019.1575356
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Sexuality in premature ovarian insufficiency

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Cited by 43 publications
(26 citation statements)
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“…POI is a life-changing diagnosis carrying a high risk of psychosexual and psychosocial consequences 52 . The early hormonal deprivation contributes to the impairment of central and peripheral components of the sexual response, resulting in hypoactive sexual desire disorder and symptomatic vulvovaginal atrophy (VVA)/genitourinary syndrome of menopause 53 . Significant emotional and cognitive 'rebuilding' is required due to the multiple effects of POI, including infertility, potential early aging, and reduced self-esteem 54 .…”
Section: Psychosexual and Psychosocial Health In Women With Prematurementioning
confidence: 99%
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“…POI is a life-changing diagnosis carrying a high risk of psychosexual and psychosocial consequences 52 . The early hormonal deprivation contributes to the impairment of central and peripheral components of the sexual response, resulting in hypoactive sexual desire disorder and symptomatic vulvovaginal atrophy (VVA)/genitourinary syndrome of menopause 53 . Significant emotional and cognitive 'rebuilding' is required due to the multiple effects of POI, including infertility, potential early aging, and reduced self-esteem 54 .…”
Section: Psychosexual and Psychosocial Health In Women With Prematurementioning
confidence: 99%
“…Psychosexual and psychosocial symptoms in POI deserve more research in order to understand the complexity of factors involved in the burden of the condition and to establish a tailored treatment with hormonal and non-hormonal strategies in the long term 53,74 . Clinical judgment has to guide the choice of treatment with the aim of counteracting, whenever possible, androgen insufficiency 53 , either by prescribing transdermal estradiol at an adequate dosage 75 and/ or by using transdermal testosterone at the dosage typical of the physiological premenopausal range 76,77 . Other pharmacological and non-pharmacological treatments are identical to those used in typical postmenopausal women.…”
Section: Optimizing Psychosexual and Psychosocial Healthmentioning
confidence: 99%
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“…Indeed, endocrine chemotherapy, surgery and/or radiation may induce profound changes at urogenital levels which have to be timely recognized in the oncologic care (76, 77). Moreover, we lack data on VVA/GSM in women with spontaneous premature ovarian insufficiency, even though it is likely that the condition is more distressing due to the younger age of these patients (78). Older women and those who abstain from sexual activity may suffer even more of VVA/GSM with vaginal and introital stenosis, fusion of the labia minora to the labia majora, and other urogenital conditions (79).…”
Section: Key-elements Of Vva/gsm Diagnosismentioning
confidence: 99%
“…[ 23 ] Notwithstanding, nonhormonal alternatives such as lifestyle changes, psychosomatic techniques, diet management and supplementation, prescription therapy, and other strategies are, however, still available and useful. [ 24 ] These are nonhormonal alternatives. Many complementary and alternative therapies lack sufficient, high-quality evidence to support their prevention and treatment under different conditions.…”
Section: Introductionmentioning
confidence: 99%