SFE of Derris elliptica (Wallich) Benth. roots: Influence of process parameters on yield and purity of rotenone

Extraction of rotenoids from Derris elliptica using supercritical CO2

“…According to the previous calculations and results, a possible strategy could be to perform a fractional extraction of the vegetable matter, operating at relatively low pressures to obtain a reasonable SC‐CO 2 solvent power towards rotenone and related active principles and enough selectivity to reduce the co‐extraction of higher molecular weight compounds. Therefore, in this work, SC‐CO 2 extraction of the active compounds from Derris root powder was performed in two steps, operating at 100 and 200 bar and at 40 °C (CO 2 density 0.62 and 0.80 g cm −3 , respectively), using a CO 2 flow rate of 0.8 kg h −1 or of 1.2 kg h −1 .…”

“…Supercritical fluid extraction (SFE) has been proposed as an environmentally friendly (green) alternative to the extraction of active principles from types of several vegetable matter . The main advantage of this process over the traditional alternatives, is control over the extract composition by changing the supercritical (SC)‐CO 2 solvent power.…”

“…The largest rotenone concentration in the extract was obtained working at 30 °C and 240 bar, whereas the highest yield of rotenone was obtained at 60 °C and 220 bar. D'Andrea et al . performed SC‐CO 2 extraction of rotenone from D. elliptica , using, as operative parameters, pressures from 90 to 440 bar and temperatures from 40 to 60 °C.…”

Assessment of population genetic diversity of Derris elliptica (Fabaceae) in China using microsatellite markers

“…(Fabaceae) is commonly used in traditional medicine (Sukrong et al, 2006). Juice from its stems and roots is used as an insecticide (Andrea et al, 2007), molluscicide (Dos Santos and Sant'Ana, 2000) and fish poison (Lu et al, 2008). Some other bioactive properties, such as antifungal (Fang et al, 2010), antihypertension effect (Dos Santos and Sant'Ana, 2000) and antitumor activity (Chun et al, 2003) have also been confirmed.…”

“…Some other bioactive properties, such as antifungal (Fang et al, 2010), antihypertension effect (Dos Santos and Sant'Ana, 2000) and antitumor activity (Chun et al, 2003) have also been confirmed. The plant is mainly cultivated in the tropics for its roots, a source of the botanical insecticide rotenone (Andrea et al, 2007;Lu et al, 2008;Wu et al, 2012b). In China, D. elliptica was introduced from different Southeast Asian countries beginning in the early decades of the last century (Li and Wang, 2010), and was mainly cultivated in Guangdong and Guangxi Provinces as a raw material for the commercial manufacture of rotenone.…”