Shape and Enhancement Analysis as a Useful Tool for the Presentation of Blood Hemodynamic Properties in the Area of Aortic Dissection

Polańczyk, Andrzej; Piechota-Polańczyk, Aleksandra; Stefańczyk, Ludomir; Strzelecki, Michał

doi:10.3390/jcm9051330

Cited by 6 publications

(6 citation statements)

References 46 publications

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“…Contrast was included in the radiological diagnosis. As the total concentration of contrast (Visipaque) during one AngioCT analysis was constant (1.5 mL per 1 kg of body weight) in the aorta, we focused only on the distribution of brightness in whole domain for the aorta’s reconstruction [ 27 ]. Medical data was retrospectively collected after obtaining written informed consent to participate in the study and were anonymized before analysis.…”

Section: Methodsmentioning

confidence: 99%

Spatial Configuration of Abdominal Aortic Aneurysm Analysis as a Useful Tool for the Estimation of Stent-Graft Migration

et al. 2020

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The aim of this study was to prepare a self-made mathematical algorithm for the estimation of risk of stent-graft migration with the use of data on abdominal aortic aneurysm (AAA) size and geometry of blood flow through aneurysm sac before or after stent-graft implantation. AngioCT data from 20 patients aged 50–60 years, before and after stent-graft placement in the AAA was analyzed. In order to estimate the risk of stent-graft migration for each patient we prepared an opposite spatial configuration of virtually reconstructed stent-graft with long body or short body. Thus, three groups of 3D geometries were analyzed: 20 geometries representing 3D models of aneurysm, 20 geometries representing 3D models of long body stent-grafts, and 20 geometries representing 3D models of short body stent-graft. The proposed self-made algorithm demonstrated its efficiency and usefulness in estimating wall shear stress (WSS) values. Comparison of the long or short type of stent-graft with AAA geometries allowed to analyze the implants’ spatial configuration. Our study indicated that short stent-graft, after placement in the AAA sac, generated lower drug forces compare to the long stent-graft. Each time shape factor was higher for short stent-graft compare to long stent-graft.

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Section: Methodsmentioning

confidence: 99%

Spatial Configuration of Abdominal Aortic Aneurysm Analysis as a Useful Tool for the Estimation of Stent-Graft Migration

et al. 2020

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“…Despite optimal medical management, a subset of these patients will develop aneurysmal degeneration [11]. Our previous results showed that each time a connection of the true and false duct appeared, the true duct had lower brightness compared to the common duct and false duct, and the false duct was characterized by higher brightness [19]. Current results indicated that the parameters derived from CFD simulations on patient-specific aortic dissection geometries strongly correlate to medical data derived from such patients.…”

Section: Discussionmentioning

confidence: 69%

“…It was noticed that each time a connection of the true and false duct appeared, the true duct had lower brightness compared to the common duct and false duct. Also, false duct was characterized by higher brightness if compared to common duct [19]. Therefore, the aim of the study was to prepare a CFD model of chosen blood flow parameters within the aorta and aortic branches in patients with type B aortic dissection before and after a thoracic endovascular aortic repair procedure.…”

Section: Introductionmentioning

confidence: 99%

Computational Fluid Dynamic Technique for Assessment of How Changing Character of Blood Flow and Different Value of Hct Influence Blood Hemodynamic in Dissected Aorta

et al. 2021

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Using computer tomography angiography (CTA) and computational structural analysis, we present a non-invasive method of mass flow rate/velocity and wall stress analysis in type B aortic dissection. Three-dimensional (3D) computer models of the aorta were calculated using pre-operative (baseline) and post-operative CT data from 12 male patients (aged from 51 to 64 years) who were treated for acute type B dissection. A computational fluid dynamics (CFD) technique was used to quantify the displacement forces acting on the aortic wall in the areas of endografts placement. The mass flow rate and wall stress were measured and quantified using the CFD technique. The CFD model indicated the places with a lower value of blood velocity and shear rate, which corelated with higher blood viscosity and a probability of thrombus appearance. Moreover, with the increase in Hct, blood viscosity also increased, while the intensity of blood flow provoked changing viscosity values in these areas. Furthermore, the velocity gradient near the tear surface caused high wall WSS; this could lead to a decreased resistance in the aorta’s wall with further implications to a patient.

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“…CFD simulations based on patient-specific models may provide insight into the biomechanical behavior of blood flow, allowing quantitative analysis of hemodynamic patterns, and predicting clinical progression. However, its clinical value still requires verification [22]. Depending on the type of problem analyzed, blood maybe reconstructed as Newtonian or non-Newtonian [23].…”

Section: Introductionmentioning

confidence: 99%

Computational Fluid Dynamics as an Engineering Tool for the Reconstruction of Endovascular Prosthesis Endoleaks

et al. 2022

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Background and objectives: Endovascular prosthesis placement is a predominant surgical procedure to reduce the risk of aneurysm rupture in abdominal aortic aneurysm patients. The formation of an endoleak is a major complication of stent-graft placement. Therefore, the aim of this study was to determine the influence of stent-graft's spatial configuration on the risk of leakage under realistic flow conditions. Materials and Methods: We analyzed data collected from 10 male patients 55±3 years old after CTA who had undergone endovascular treatment. Computational Fluid Dynamics technique was applied for the reconstruction of blood hemodynamic. Two cases of the stent-graft were analyzed each time, with and without the endoleak, reconstructed from one patient data with the endoleak. Endoleak-free geometries were prepared by virtual closure of the opening. Results: It was observed that high value of the blood velocity around the endoleak may provoke its slowly rupture, which may increase the blood flow to the aneurysm sack in the case of type II endoleaks. Moreover, the appearance of endoleak reduces the average blood velocity in the entire stent-graft which in some cases may contribute to blood coagulation. Furthermore, no clot can form at the site of the endoleak due to the high value of wall shear stress near of the endoleak which prevents thrombosis.

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Shape and Enhancement Analysis as a Useful Tool for the Presentation of Blood Hemodynamic Properties in the Area of Aortic Dissection

Cited by 6 publications

References 46 publications

Spatial Configuration of Abdominal Aortic Aneurysm Analysis as a Useful Tool for the Estimation of Stent-Graft Migration

Spatial Configuration of Abdominal Aortic Aneurysm Analysis as a Useful Tool for the Estimation of Stent-Graft Migration

Computational Fluid Dynamic Technique for Assessment of How Changing Character of Blood Flow and Different Value of Hct Influence Blood Hemodynamic in Dissected Aorta

Computational Fluid Dynamics as an Engineering Tool for the Reconstruction of Endovascular Prosthesis Endoleaks

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