A fundamental challenge in physics is controlling the propagation of waves in disordered media despite strong scattering from inhomogeneities. Spatial light modulators enable one to synthesize (shape) the incident wavefront, optimizing the multipath interference to achieve a specific behavior such as focusing light to a target region. However, the extent of achievable control was not known when the target region is much larger than the wavelength and contains many speckles. Here we show that for targets containing more than g speckles, where g is the dimensionless conductance, the extent of transmission control is substantially enhanced by the long-range mesoscopic correlations among the speckles. Using a filtered random matrix ensemble appropriate for coherent diffusion in open geometries, we predict the full distributions of transmission eigenvalues as well as universal scaling laws for statistical properties, in excellent agreement with our experiment. This work provides a general framework for describing wavefront-shaping experiments in disordered systems.Waves propagating through a disordered medium undergo multiple scattering from the inhomogeneities. Interference among the multiply scattered fields has important consequences that cannot be described with incoherent diffusion 1,2 . By controlling the incident wave ("wavefront shaping," WFS), one can manipulate this interference and drastically modify the transport of light, microwaves, and acoustic waves 3 . One early and notable example is focusing light onto a local speckle-sized target through aligning the scattered fields there 4-7 , which has led to advances in imaging within biological tissue and other scattering materials 8 . The transport through disordered structures is described by a random field transmission matrix, and the use of WFS over such local properties has treated the matrix elements as having only short-range correlations on the scale of a single speckle 4,9-13 . However, it has long been known that diffusive waves also exhibit long-range and infinite-range correlations 14-17 ; this was previously noted in the context of electron transport through mesocopic structures, where correlations lead to anomalously large conductance fluctuations 18 . The long-range correlations are related to the existence of near-unity-transmission input states ("open channels") 19-24 , and have measurable effects on other global statistical properties of diffusive waves such as the total transmission variance 25-28 , the increased background for maximally focused waves [29][30][31][32] , and the singular values of large transmission matrices [33][34][35][36] . With the rapid growth of WFS, an important question, both scientifically and technologically, is how correlations affect the coherent control over targets larger than a single speckle and smaller than the full transmitted pattern, i.e. in between local and global. This intermediate regime remains poorly understood but is relevant for many applications ranging from telecommunications and cryptography to...