The inverse finite element method (iFEM) for the 3D framework deformation reconstruction was introduced. As the process of iFEM did not require a priori knowledge, such as the modal shape, the loading, and the elastic-inertial material information of the structure, it presented high potential in the framework deformation reconstruction. With the current research, it was observed that the key step in the deformation reconstruction of the frame structure with iFEM was the section strains computing of the beam element from the surface strain measurements. The corresponding stability was severely affected by the placement of strain sensors. Therefore, it was necessary to discover a suitable sensor placement to maintain the stability of section strains computing. For this problem, one optimal model of sensor placement was proposed in this paper. Firstly, the well-separated eigenvalues were applied as the optimization target to construct the optimal model. Following, an optimal sensor placement was obtained through the optimal placement model solution, with the particle swarm optimization (PSO) method. Finally, the effectiveness of optimal placement was verified though the accuracy comparison of iFEM deformation reconstruction of a wing-like frame subjected to various loads for different schemes of sensor placement.