Share Page: Share on facebook Share on twitter Share on email Share on google_plusone_share More Sharing Services Back Volume 34 , Issue 1 January/February 2014 Pages e1–e8 Interdisciplinary Approach for Treating a Large Through-and-Through Periapical Defect Using Guided Tissue Regeneration: A Case Report

Abstract

A number of diagnostic and management challenges exist for achieving complete regeneration of large through-and-through periapical lesions. An unfavorable endodontic outcome may occur as a result of uncontrolled infection or unpredictable bone healing. This article presents a case with a 15 × 15-mm through-and-through periapical lesion and persistent gingival swelling. Endodontic microsurgery and guided tissue regeneration were performed using a resorbable membrane and osseous substitute. A 2-year postoperative radiograph revealed complete resolution of the periapical radiolucency. Seven-year clinical and radiographic follow-up showed that the tooth was asymptomatic and a long-term successful outcome had been maintained.

An infrequent clinical case of mucosal fenestration: Treated with an interdisciplinary approach and regenerative therapy

“…There have been many clinical studies published where GTR therapy was used in cases of periradicular and coronoapical bone defect that have shown promising results. [456] However, these cases did not have associated soft-tissue fenestrations. Established literature does not show any long-term clinical study with a large sample size of mucosal fenestration as the finding is rare.…”

“…Use of resorbable collagen membrane used as GTR therapy has also proved to be highly successful when treating endodonticperiodontal lesions and has shown good results, relating to bone growth and connective tissue attachment. [457]…”

“…It may also be a cause of concern for esthetics and root hypersensitivity. Various techniques in earlier literature have been suggested for the treatment of such defects depending on its etiology which includes soft-tissue grafting,[23] flap procedure,[1] a combination of soft-tissue and bone grafting procedures,[2] and guided tissue regeneration (GTR) and bone grafting procedures,[456] which proved to give good results with bony defects.…”

Treatment of a large periradicular defect using guided tissue regeneration: A case report of 2 years follow-up and surgical re-entry

“…Several authors have reported the successful resolution of periapical defects with a combined application of GTR and bone grafts[ 16 17 18 19 20 ] or with GTR alone. [ 21 22 23 ] Some have resorted to combined technique of GTR and Platelet rich plasma.…”