This research study the energy absorption performance of aluminum core honeycomb sandwich panel (ACHSP) with filled and empty cores subjected to low-velocity impact testing, with diverse skins; (i) aluminum sheets, (ii) 5-ply epoxy glass composite, and (iii) 5-ply shear thickening fluid (STF)-impregnated glass fabrics. The prepared STF was 35 wt% and the impactor heights was selected at 100 and 500 mm to assess the effect of different impact velocities on the energy absorption capability of STF. The specific energy absorption (SEA) of the STF-filled ACHSP with 5-ply STF-impregnated fabrics skin (height of 500 mm) compared to STF-filled ACHSP with aluminum sheets skin and 5-ply epoxy glass composite skin have increased by 28.38 and 21.79%, respectively. In a fact of truth, when the external force is applied to the STF-filled ACHSP, the fluid transitions from a low-velocity to a high-velocity state instantly. This transition exerts forces on the suspended particles within the fluid. Actually, during the impact, the particles come into close contact and form temporary particle networks or chains. These networks increase the viscosity of the fluid, making it resistant to flow. The energy of the impact is then absorbed by the formation and reformation of these particles’ networks. However, the SEA of STF-filled ACHSP at the height of 500 mm to empty ACHSP at the height of 100 mm have decreased significantly, and the energy absorption of STF-filled ACHSPs to corresponding empty ACHSPs have increased remarkably.