Shedding a light on the importance of photopatch testing: A 12‐year experience in a dermatology unit

Codeço, Carlos; Alves, Pedro Botelho; Figueiredo, Ana; Flor, Duarte; Gonçalo, Margarida

doi:10.1111/cod.14297

Cited by 7 publications

(3 citation statements)

References 29 publications

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“…The best diagnostic method currently available for PACD is photopatch testing. 8 At present the various photopatch series available are, 8,9 German, Austrian, and Swiss Photopatch Test series; The Scandinavian photopatch test series;European photopatch test series and North American standard photopatch test series. In our study we used the Indian Standard Series (ISS) for our photopatch tests.…”

Section: Discussionmentioning

confidence: 99%

Correlation of photopatch positivity with clinical profile in patients with photoallergic dermatitis

Nirmaladevi,

Kayalvizhi,

Sivayadevi

et al. 2024

IJCED

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Photopatch test (PPT) is designed to diagnose Photoallergic Contact Dermatitis (PACD) using specific dose and wavelength of irradiation. This study is a retrospective analysis of patients with photosensitivity who have undergone photopatch testing. To find the Correlation of photo patch positivity with clinical profile in patients with photoallergic dermatitis. Photo patch testing helps in determining the sensitizing potentials of commonly used day to day agents containing the allergen. Thirty-seven patients who had patch tested between July 2022and June 2023 were analyzed. The patch test antigens comprising 20 common photoallergens from Indian Standard Series were photopatch tested. Of all the patients tested the overall positivity rate was (67.56%). All patients had a characteristic clinical picture of photodermatitis for an variable duration. All patients were engaged in various occupations that involved working outdoors. The exacerbating factors were summer season in 15 (40.54%) patients, insecticides spraying in three (8.1%) and exposure to plant in ten (27%). History of contact with cement was present in six (16.21%) patients. The patients who showed positivity after irradiation was 5 (13.51 %), before and after irradiation was 7 (18.91%), and exacerbated grading after irradiation was 13 (35.13%). The commom allergen showing positivity were parthenium (29.72%), potassium dichromate (13.51%), PPD (10.81%). Apart from these allergens’ fragrance mix, paraben, neomycin sensitivity was also noted in few patients. Significant number of cases belongs to photodermatitis, thereby, finding the cause and the measures to alleviate the symptoms are paramount important. For proper diagnosis, photopatch test is essential and our study emphasis the same which can aid in appropriate management. Cosmetics, sunscreens and drugs like NSAID are found to be the emerging cause for PACD and photopatch series with relevence to above allergen is the need of the hour.

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Section: Discussionmentioning

confidence: 99%

Correlation of photopatch positivity with clinical profile in patients with photoallergic dermatitis

Nirmaladevi,

Kayalvizhi,

Sivayadevi

et al. 2024

IJCED

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“…● physiological dysfunction or direct tissue damage that can be proved by physicochemical testing; photopatch testing for photoallergic reactions provides an example, if accompanied by proper control procedures to avoid the problems of false positive and false negative results9; this is analogous to recreating the crime scene in the presence of the suspect;…”

Section: Between-the-eyes Reactionsmentioning

confidence: 99%

When I use a word . . . Medical definitions: Pharmacovigilance signals

Aronson

2023

BMJ

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In seeking evidence of adverse drug effects and adverse drug reactions, those working in pharmacovigilance recognise the phenomenon of a signal that raises the suspicion of a causal relation between a drug and an adverse effect or reaction. Manfred Hauben and I, based on etymology, usage, previous definitions, and the processes involved, have defined a signal of suspected causality as follows: signal of suspected causalityn. information that arises from one or multiple sources (including observations and experiments), which suggests a new potentially causal association, or a new aspect of a known association, between an intervention and an event or set of related events, either adverse or beneficial, which would command regulatory, societal, or clinical attention, and is judged to be of sufficient likelihood to justify verificatory and, when necessary, remedial actions This definition, with small variations, was republished by the Council for International Organizations of Medical Sciences (CIOMS) in 2010 and was adopted by one of its working groups in 2020. We take this as a signal of approval of the definition.

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“…Photopatch could be a valuable adjunctive testing for the differential diagnosis. 5 In conclusion, DIP is a rare and serious dronedarone-related adverse reaction. Patients taking dronedarone should be advised to wear proper sun protection.…”

mentioning

confidence: 94%