2023
DOI: 10.3390/ijms24032262
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Shedding Light on the Pathogenesis of Splanchnic Vein Thrombosis

Abstract: Splanchnic vein thrombosis is a rare but potentially life-threatening manifestation of venous thromboembolism, with challenging implications both at the pathological and therapeutic level. It is frequently associated with liver cirrhosis, but it could also be provoked by myeloproliferative disorders, cancer of various gastroenterological origin, abdominal infections and thrombophilia. A portion of splanchnic vein thrombosis is still classified as idiopathic. Here, we review the mechanisms of splanchnic vein th… Show more

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Cited by 5 publications
(16 citation statements)
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“…A significant proportion of patients, however, are asymptomatic and diagnosed incidentally with SVT when undergoing routine imaging for other conditions, most commonly malignancies and cirrhosis. 3,50,51 Incidentally detected SVTs have been found in 1.7% of abdominal CT scans and, in different cohort studies, they constitute 30 to 59% of all SVTs. [52][53][54]…”
Section: Risk Factorsmentioning
confidence: 99%
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“…A significant proportion of patients, however, are asymptomatic and diagnosed incidentally with SVT when undergoing routine imaging for other conditions, most commonly malignancies and cirrhosis. 3,50,51 Incidentally detected SVTs have been found in 1.7% of abdominal CT scans and, in different cohort studies, they constitute 30 to 59% of all SVTs. [52][53][54]…”
Section: Risk Factorsmentioning
confidence: 99%
“…1,2 SVT commonly occurs in the context of liver disease, such as cirrhosis, and malignancies. 3 Other causes include intraabdominal surgery or infections, pancreatitis, inflammatory bowel diseases, thrombophilia, and myeloproliferative neoplasms (MPNs). 3,4 Anticoagulation is the cornerstone of SVT management, intended to prevent thrombus extension and recurrent thrombosis, while carefully balancing the risk of hemorrhage.…”
Section: Introductionmentioning
confidence: 99%
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