Shellfish consumption: A major risk factor for colorectal cancer

Manerio, Emilia; Rodas, Victoria López; Costas, Eduardo; Hernández, Juan Martínez

doi:10.1016/j.mehy.2007.03.041

Cited by 63 publications

(33 citation statements)

References 25 publications

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“…Segundo trabalhos de Lopez-Rodas (2006) e Manerio et al (2008), as toxinas DSP parecem se comportar como agentes cancerígenos, principalmente em casos de câncer de colo retal. Tabela 1 -Lista de espécies e sua ocorrência no parque de maricultura em AI e PA, Penha, SC.…”

Section: Discussionunclassified

Ocorrência de dinoflagelados tecados potencialmente tóxicos e nocivos em cultivos de moluscos situados no município de Penha, SC

Miotto¹,

Tamanaha²

2012

Braz. J. Aquat. Sci. Technol.

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The purpose of this study was to describe the composition and occurrence of potentially toxic and harmful species of thecate dinoflagellates in cultured shellfish, located at Armação do Itapocorói (AI) and Praia Alegre (PA) in the municipality of Penha, SC -Brazil. Water samples were collected and environmental parameters (salinity, water temperature and depth of Secchi disk) were determined weekly between April 2007 and April 2008 at two sites by a monitoring program maintained by the Laboratory for the Study of Harmful Algae, CTTMar, UNIVALI. The identification of the organisms was made through an Olympus microscope, model BX41 with up to 1000x. During the sampling period, we identified 21 species of thecate dinoflagellates potentially toxic and harmful in the genus Alexandrium, Ceratium, Dinophysis and Prorocentrum. The species P. obtusum (86%), D. acuminata (78.5%) and P. micans (72%) were very frequent throughout the period in the two sample points. The point with highest species richness was the AI, with 14 species, and the PA had the lowest richness with only two species. Most samples were considered rare relative to the abundance of thecate dinoflagellates compared to the presence of harmful microalgae, but during the month of September 2007, were considered abundant, during which there was a bloom of D. acuminata. The similarity between the two points throughout the sampling period reached a high coefficient (86%), and between the months examined, June 2007 showed the lowest similarity (10%) and July 2007 the greatest similarity recorded (91%). The composition and distribution of thecate dinoflagellates during the study showed that the existence of a dynamic community structure could be used as a tool to aid the monitoring of harmful algae mariculture activity in this region.

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Section: Discussionunclassified

Ocorrência de dinoflagelados tecados potencialmente tóxicos e nocivos em cultivos de moluscos situados no município de Penha, SC

Miotto¹,

Tamanaha²

2012

Braz. J. Aquat. Sci. Technol.

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“…For example, several studies have indicated that repetitive exposure to low level doses of OA through shellfish consumption may be correlated to an increase in the incidence of colorectal cancers in exposed human populations [78][79][80]. Developmental and neurological effects of chronic (low-level) DA exposure on infants and young children are a concern, as DA has been shown to cross the placenta, enter the blood brain barrier of infants, and collect in amniotic fluid in mammals [81][82][83][84][85].…”

Section: Human Health Effectsmentioning

confidence: 99%

Investigation of Algal Biotoxin Removal during SWRO Desalination through a Materials Flow Analysis

Manheim

Jiang

2017

Water

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Abstract:The operation of seawater reverse osmosis (SWRO) desalination facilities has become challenged by the increasing frequency and severity of harmful algal blooms (HABs). The efficiency of algal toxins removal during SWRO and pretreatment processes has critical human health implications. Therefore, a probabilistic materials flow analysis (pMFA) was developed to predict the removal of algal toxins in source water by various pretreatment configurations and operations during SWRO desalination. The results demonstrated that an appreciable quantity of toxins exists in the SWRO permeate (ng/L-µg/L levels), the backwash of pretreatment, and final brine rejects (µg/L-mg/L levels). Varying the pretreatment train configuration resulted in statistically significant differences in toxin removals, where higher removal efficiencies were evidenced in systems employing microfiltration/ultrafiltration (MF/UF) over granular media filtration (GMF). However, this performance depended on operational practices including coagulant addition and transmembrane pressures of MF/UF systems. Acute human health risks during lifetime exposure to algal toxins from ingestion of desalinated water were benign, with margins of safety ranging from 100 to 4000. This study highlights the importance of pretreatment steps during SWRO operation in the removal of algal toxins for managing marine HABs.

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“…It is a potent tumour promoter that is not an activator of protein kinase C, but is a powerful inhibitor of protein phosphatases-1 and -2A (PP1 and PP2A) in vitro ( Haystead et al, 1989). DSP toxins are tumour promoters that could increase colorectal cancer (CRC) risk (Manerio et al, 2008).…”

Section: Diarrhetic Shellfish Poisoning (Dsp)mentioning

confidence: 99%

Seafood Toxins and Poisonings

Kılınç¹

2015

IU J Fish Aquatic Sci

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Seafood poisoning is the foodborne illness associated with the consumption of shellfish and fish that contain toxins. Shellfish toxins are produced by certain dinoflagellate species. Bivalve shellfish, especially mussels, clams and oyster can accumulate so many toxins by ingesting with filter-feeding. Shellfish have mechanisms that prevent the hazardous effects of these toxins. Although the toxins do apparently not harm the shellfish and fish, humans eating toxic seafood may become poisoned. These toxins can not be eliminated by cooking procedures. Toxins that cause poisining on fish are produced by spoilage bacteria. The deterioration of fish (tuna, sardine etc.) causes toxins to occur. Seafood poisoning (paralytic shellfish poisoning (PSP), ciguatera poisoning, scombroid poisoning, etc.) is a serious illness and the toxins (saxitoxin, tetrodotoxins, etc.) that are responsible for this illness pose a great risk to seafood safety and public health. Paralytic shellfish poisoning (PSP) and scombroid poisoning are common seafood toxicity problems. The inability of finding an antidote for seafood poisoning makes this foodborne illness even more serious. By waiting shellfish in clean water to obtain the reduction on toxin levels can be the solution for protection from poisoning. In this review, the characteristics of toxins and their effects on human health are discussed. Keywords SU ÜRÜNLERİ TOKSİNLERİ VE ZEHİRLENMELERİ ÖZSu ürünleri zehirlenmeleri, toksinleri içeren balık ve kabuklu su ürün-lerinin tüketimiyle oluşan besin kaynaklı hastalıktır. Kabuklu su ürünleri toksinlerini bazı dinoflagellata türleri üretirler. Çift kabuklular, özellikle midye, istiridye ve deniz tarağı süzerek beslenme yaparak birçok toksini biriktirirler. Kabuklu su ürünleri, bu toksinlerin tehlikeli etkilerini önle-yici mekanizmaya sahiptir. Toksinlerin kabuklu su ürünlerinde ve balık-larda zararlı etkilerinin olmamasına rağmen, toksin içeren su ürünlerini yiyen kişiler için zehirli olabilir. Bu toksinler, pişirme işlemleri ile giderilemezler. Balık zehirlenmesine sebep olan toksinler bozulma bakterileri tarafından üretilir. Balık (tuna, sardalya vb.) bozulması toksinlerin ortaya çıkmasına sebep olur. Su ürünleri zehirlenmeleri (paralitik kabuklu su ürü-nü zehirlenmesi (PSP), ciguatera balık zehirlenmesi, skombroid zehirlenmesi, vb.) ciddi bir hastalıktır ve bu hastalığın sorumlusu olan toksinler (saksitoksin, tetradotoksin, vb.), su ürünleri güvenliği ve halk sağlığı için büyük bir risk yaratır. Paralitik kabuklu su ürünü zehirlenmesi (PSP) ve skombroid zehirlenmesi, en sık görülen su ürünleri zehirlenmeleridir. Su ürünleri zehirlenmesi için bir antidot bulunmaması, bu besin kaynaklı hastalığı daha da ciddi şekle getirir. Kabuklu su ürünleri toksin seviyelerinin azalması için, temiz suda bekletme, zehirlenmeden korunmak için çözüm olabilir. Bu incelemede, toksinlerin karakteristikleri ve insan sağlığına etkileri tartışılmıştır.Anahtar kelimeler: Su ürünleri toksinleri, kabuklu su ürünleri, balık, su ürünleri zehirlenmeleri.

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Shellfish consumption: A major risk factor for colorectal cancer

Cited by 63 publications

References 25 publications

Ocorrência de dinoflagelados tecados potencialmente tóxicos e nocivos em cultivos de moluscos situados no município de Penha, SC

Ocorrência de dinoflagelados tecados potencialmente tóxicos e nocivos em cultivos de moluscos situados no município de Penha, SC

Investigation of Algal Biotoxin Removal during SWRO Desalination through a Materials Flow Analysis

Seafood Toxins and Poisonings

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