Shewanella algae infection in Italy: report of 3 years' evaluation along the coast of the northern Adriatic Sea

Torri, Arianna; Bertini, S.; Schiavone, Pasqua; Congestrì, Francesco; Matteucci, Matteo; Sparacino, Monica; Testa, G.; Pedna, Maria Federica; Sambri, Vittorio

doi:10.1016/j.nmni.2018.01.002

Cited by 24 publications

(28 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is probably due to the fact that they are still unknown and not reported on databases. Considering the data reported in literature, very high MICs were observed by Torri and coworkers [73] in clinical S. algae isolates during an Italian survey on shewanella-associated infections. This is probably an intrinsic resistance present in S. algae strains whose gene may be chromosomal-encoded considering a few presence of plasmids in these strains.…”

Section: Discussionmentioning

confidence: 87%

Resistome, Mobilome and Virulome Analysis of Shewanella algae and Vibrio spp. Strains Isolated in Italian Aquaculture Centers

et al. 2020

View full text Add to dashboard Cite

Antimicrobial resistance is a major public health concern restricted not only to healthcare settings but also to veterinary and environmental ones. In this study, we analyzed, by whole genome sequencing (WGS) the resistome, mobilome and virulome of 12 multidrug-resistant (MDR) marine strains belonging to Shewanellaceae and Vibrionaceae families collected at aquaculture centers in Italy. The results evidenced the presence of several resistance mechanisms including enzyme and efflux pump systems conferring resistance to beta-lactams, quinolones, tetracyclines, macrolides, polymyxins, chloramphenicol, fosfomycin, erythromycin, detergents and heavy metals. Mobilome analysis did not find circular elements but class I integrons, integrative and conjugative element (ICE) associated modules, prophages and different insertion sequence (IS) family transposases. These mobile genetic elements (MGEs) are usually present in other aquatic bacteria but also in Enterobacteriaceae suggesting their transferability among autochthonous and allochthonous bacteria of the resilient microbiota. Regarding the presence of virulence factors, hemolytic activity was detected both in the Shewanella algae and in Vibrio spp. strains. To conclude, these data indicate the role as a reservoir of resistance and virulence genes in the environment of the aquatic microbiota present in the examined Italian fish farms that potentially might be transferred to bacteria of medical interest.

show abstract

Section: Discussionmentioning

confidence: 87%

Resistome, Mobilome and Virulome Analysis of Shewanella algae and Vibrio spp. Strains Isolated in Italian Aquaculture Centers

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Many labs in the past were not able to distinguish Shewanella putrefaciens and algae. Over the past decade, the use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry has enabled detection of the latter and thus we see an increasing number of infections caused by Shewanella algae [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Shewanella algae – A Novel Organism Causing Bacteremia: A Rare Case and Literature Review

Bernshteyn¹,

Kumar²,

Joshi³

2020

Cureus

View full text Add to dashboard Cite

Shewanella species are distributed ubiquitously in the soil and water, being common in the marine habitat. Although these bacilli were thought to be rarely pathogenic, there has been an increasing number of reports of them being implicated in a wide variety of clinically significant infections. Three distinct species were initially recognized by MacDonell and Colwell. They were Shewanella putrefaciens, hanedai and benthica. Shewanella algae, which is the most common human clinical isolate, was believed to be a strain of Shewanella putrefaciens by some authors, and was later grouped as a separate and distinct entity. With multi-drug resistance on the rise and the lack of large-scale systemic studies, we describe a case of bacteremia caused by this rare organism. We hope to increase the awareness among care providers on the same.

show abstract

“…Torri et al. in 2017 published a case series of 17 patients with Shewanella infection in Italy [18]. Among these patients, five (29.4%) had a SSTI and another five (29.4%) had sepsis.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, to support the significance of seawater exposure in the pathogenesis of the Shewanella infection, Tori et al reported that two patients in the sepsis group and four patients in the SSTI group, respectively, had contact with seawater within previous four weeks. The only patient who died had Shewanella positive blood cultures and sepsis [18].…”

Section: Discussionmentioning

confidence: 99%

“…Shewanella causes four major types of infection: (i) septicemia, (ii) skin and soft tissue infections (SSTI), varying from mild cellulitis to severe life-threatening necrotizing fasciitis, (iii) hepatobiliary infections, and (iv) ear infections [6-16]. Risk factors for infection include mainly mucocutaneous abrasions or penetrating traumas with marine exposure or consumption of seafood [5, 10, 14, 17, 18]. The prospect of developing the illness due to S. algae is highest in patients with vascular conditions, diabetes, hepatobiliary disease, malignancy and otherwise immunocompromised [6, 9, 10, 15].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Severe Sepsis and Wet Gangrene Requiring Foot Amputation Caused by an Emerging Human Pathogen – Shewanella algae

Talbot¹,

Amble²,

Delva³

et al. 2019

Cureus

View full text Add to dashboard Cite

A 69-year-old woman with type 2 diabetes mellitus, peripheral vascular disease, and other comorbidities presented with recurrent syncopal episodes. Cellulitic skin changes in her right lower extremity were noted, as well as a large hemorrhagic bulla on the dorsum of her right foot. Severe sepsis was determined to be the reason for her syncopal episodes. Blood cultures and the bulla aspirate culture were positive for Shewanella algae that was pan-sensitive to antibiotics. Her clinical status was stabilized with a regimen of intravenous fluids and broad-spectrum antibiotics. However, due to the development of right foot gangrene, she underwent debridement and eventually required transmetatarsal open amputation.

show abstract

Shewanella algae infection in Italy: report of 3 years' evaluation along the coast of the northern Adriatic Sea

Cited by 24 publications

References 31 publications

Resistome, Mobilome and Virulome Analysis of Shewanella algae and Vibrio spp. Strains Isolated in Italian Aquaculture Centers

Resistome, Mobilome and Virulome Analysis of Shewanella algae and Vibrio spp. Strains Isolated in Italian Aquaculture Centers

Shewanella algae – A Novel Organism Causing Bacteremia: A Rare Case and Literature Review

Severe Sepsis and Wet Gangrene Requiring Foot Amputation Caused by an Emerging Human Pathogen – Shewanella algae

Contact Info

Product

Resources

About