Shift Work as a Cardiovascular Disease Risk Factor: A Narrative Review

Wong, Ryan; Crane, Alex; Sheth, Jay; Mayrovitz, Harvey N.

doi:10.7759/cureus.41186

Cited by 4 publications

(3 citation statements)

References 53 publications

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“…Studies suggest that shift workers have a 40% higher risk of developing CVDs compared to those who work regular hours (D. Wang et al, 2018). The hypotheses for this relationship include the disruption of circadian rhythms, changes in physical and mental well-being, and negative impacts on family life and lifestyle habits, such as physical activity and diet (Ho et al, 2022;Wong et al, 2023).…”

Section: Discussionmentioning

confidence: 99%

Food consumption patterns and cardiovascular risk among shift workers: A NOVA-based approach

Silva,

Ribeiro,

de Freitas

et al. 2024

Preprint

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Objective: To evaluate the association between food consumption, by extent and purpose of processing, and cardiovascular disease (CVD) risk among rotating shift workers. Methods: The cross-sectional study included 213 male shift workers. Dietary intake was assessed using a 24-hour recall method conducted by trained interviewers. Food items were classified using two approaches: the first was based on the quantity consumed from each food group. Fruits and vegetables (FV) intake, is classified as recommended at 400g per day by WHO guidelines. Ultraprocessed foods (UPFs) were analyzed based on tertiles of daily caloric contribution. The second approach, the NOVA dietary diversity score (DDS-NOVA) assessed the variety of consumed items within each food group, assigning points for each unique item consumed, irrespective of quantity or frequency. The CVD risk was evaluated using the Framingham coronary heart disease risk score (FCRS), categorizing participants as low risk (<5%) or intermediate to high risk (>5%). Descriptive, univariate, and multivariate logistic regression were used. Results: CVD-risk was classified as high in 43.7%. In the multivariate model, the recommended consumption of FV was associated with a lower chance of high CVD-risk (OR:0.47;95%CI:0.23-0.98), and there was no association between the amount of UPF consumption and CVD-risk. In terms of variety, fresh-food consumption was associated with a lower chance of high CVD-risk (OR:0.67;95%CI:0.23-0.98), and UPF consumption was associated with higher CVD-risk (OR:1.30;95%CI:1.12-1.87). Conclusion: Consumption of both variety and quantity of fresh-foods was associated with a lower chance of CVD-risk, while a variety of consumption of UPF items increased this chance.

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Section: Discussionmentioning

confidence: 99%

Food consumption patterns and cardiovascular risk among shift workers: A NOVA-based approach

Silva,

Ribeiro,

de Freitas

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Reduced Life Expectancy: Studies have suggested that individuals engaged in non-traditional shift work may have a reduced life expectancy attributed to the increased risk of cardiovascular events and metabolic complications [ 29 , 30 ].…”

Section: Discussionmentioning

confidence: 99%

“…Occupational Safety and Performance: Cardiovascular health is critical for maintaining the safety and performance of shift workers, especially those engaged in physically demanding or high-stress occupations. Good cardiovascular function supports endurance, recovery, and resilience in the face of occupational challenges [ 29 , 41 ].…”

Section: Discussionmentioning

confidence: 99%

Tackling Shift Work: Cardiovascular Health in the Auto Industry

Bunescu,

Gheorman,

Marcu

et al. 2024

Healthcare

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Shift work, particularly in the auto industry, presents significant health challenges, notably in how it impacts cardiovascular health due to irregular work schedules and associated sleep disruptions. This prospective study evaluated 4683 workers from a single Romanian automotive enterprise to investigate the relationship between fixed shift work schedules and cardiovascular health outcomes. Our analysis focused on fixed-shift workers, excluding those on rotating shifts to reduce variability and enhance the clarity of the findings. The findings reveal that night shift workers are at a heightened risk of cardiovascular diseases (CVDs) compared to their day shift counterparts. Night shift workers demonstrated a higher CVD incidence (4.3%) compared to day shift workers (2.6%), with an odds ratio (OR) of 1.68 (95% CI: 1.08 to 2.62, p = 0.021). This association remained significant after adjusting for potential confounders, with an adjusted OR of 1.74 (95% CI: 1.09 to 2.75, p = 0.019). Male night shift workers exhibited a significantly higher CVD incidence (4.5%) compared to male day shift workers (3.0%), with an OR of 1.75 (95% CI: 1.07 to 2.89, p = 0.026). Female night shift workers also showed a higher CVD incidence (3.4%) compared to female day shift workers (1.3%), although this was not statistically significant. These findings underscore the urgent need for targeted interventions and effective strategies to mitigate these risks and promote the cardiovascular health and overall well-being of shift workers in the auto industry. This research contributes to a deeper understanding of how non-traditional work schedules affect health and provides a basis for implementing protective measures in occupational settings.

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Chronic mistimed feeding results in renal fibrosis and disrupted circadian blood pressure rhythms

Benjamin,

Pati,

Luong

et al. 2024

American Journal of Physiology-Renal Physiology

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Circadian disruption is a disturbance in biological timing which can occur within or between different organizational levels, ranging from molecular rhythms within specific cells to misalignment of behavioral and environmental cycles. Previous work from our group showed that less than one week of food restriction to the light (inactive) period is sufficient to invert diurnal blood pressure rhythms in mice. However, kidney excretory rhythms and functions remained aligned with the light-dark cycle. Shift workers have increased risk of cardiovascular disease that may different between sexes and often have irregular mealtimes making the possibility of mistimed feeding as a potential contributor to the development of kidney disease. Thus, we hypothesized that chronic mistimed food intake would result in adverse cardiorenal effects with sex-differences in severity. Here we show that chronic circadian disruption via mistimed feeding results in renal fibrosis and aortic stiffness in a sex-dependent manner. Our results indicate the importance of meal timing for maintenance of blood pressure rhythms and kidney function, particularly in males. Our results also demonstrate females are better able to acclimate to circadian-related behavioral change.

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Shift Work as a Cardiovascular Disease Risk Factor: A Narrative Review

Cited by 4 publications

References 53 publications

Food consumption patterns and cardiovascular risk among shift workers: A NOVA-based approach

Food consumption patterns and cardiovascular risk among shift workers: A NOVA-based approach

Tackling Shift Work: Cardiovascular Health in the Auto Industry

Chronic mistimed feeding results in renal fibrosis and disrupted circadian blood pressure rhythms

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