2013
DOI: 10.1152/jn.00221.2013
|View full text |Cite
|
Sign up to set email alerts
|

Shifted encoding strategy in retinal luminance adaptation: from firing rate to neural correlation

Abstract: Neuronal responses to prolonged stimulation attenuate over time. Here, we ask a fundamental question: is adaptation a simple process for the neural system during which sustained input is ignored, or is it actually part of a strategy for the neural system to adjust its encoding properties dynamically? After simultaneously recording the activities of a group of bullfrog's retinal ganglion cells (dimming detectors) in response to sustained dimming stimulation, we applied a combination of information analysis appr… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

1
11
0

Year Published

2014
2014
2022
2022

Publication Types

Select...
6
2

Relationship

1
7

Authors

Journals

citations
Cited by 16 publications
(12 citation statements)
references
References 67 publications
1
11
0
Order By: Relevance
“…Although this property appears to be consistent with findings for other gap junction–coupled neurons 39,40 , it sharply contrasts with synchrony generated by common input measured in other parts of the brain, where output correlations are found to increase with spike rate 36,37 . Correlations driven by common input are generally found to be weak at low spike rates because they are masked by the spike threshold and therefore only become evident at higher activity levels 36,37 .…”
Section: Discussionsupporting
confidence: 84%
“…Although this property appears to be consistent with findings for other gap junction–coupled neurons 39,40 , it sharply contrasts with synchrony generated by common input measured in other parts of the brain, where output correlations are found to increase with spike rate 36,37 . Correlations driven by common input are generally found to be weak at low spike rates because they are masked by the spike threshold and therefore only become evident at higher activity levels 36,37 .…”
Section: Discussionsupporting
confidence: 84%
“…Furthermore, ON and OFF RGCs have different excitatory and inhibitory synaptic inputs, which results in different spike time and spike count variability in these cells (Uzzell and Chichilnisky, 2004; Murphy and Rieke, 2006). These differences in the neural network between retinal ON and OFF pathways may induce different encoding strategies in neuronal ON and OFF responses (Zaghloul et al, 2003; Masland, 2012; Harris and Mrsic-Flogel, 2013; Xiao et al, 2013). …”
Section: Discussionmentioning
confidence: 99%
“…Experiments were performed on isolated bullfrog retinas at room temperature (22–26°C) (Jing et al, 2010; Xiao et al, 2013, 2014). Bullfrogs were dark adapted for about 30 min prior to experiments.…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…A piece of retinal tissue (~2 × 2 mm 2 ) is fixed on the MEA by a permeable membrane and perfused with oxygenated Ringer's solution (NaCl 100.0, KCl 2.5, MgCl 2 1.6, CaCl 2 1.0, NaHCO 3 18.0, Glucose 10.0 mM). Each retina preparation can last for 6–8 h for experiments (Ishikane et al, 2005; Xiao et al, 2013). Retinal activities are recorded by MEA with 200 μm inter-electrode distance and 10 μm electrode diameter (MEA60-200-10-PtBlack, Qwane Bioscience).…”
Section: Methodsmentioning
confidence: 99%