Shiitake dermatitis recorded by French Poison Control Centers – new case series with clinical observations

Boels, D.; Landreau, Anne; Bruneau, Chloé; Garnier, R.; Pulce, C.; Labadie, Magali; Haro, Luc de; Harry, P.

doi:10.3109/15563650.2014.923905

Cited by 43 publications

(67 citation statements)

References 21 publications

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“…The raw shiitake mushrooms cause toxic dermatitis by reaction to lentinan thermolabile polysaccharide[168]. Therefore, the shiitake mushrooms are recommended to be utilized after cooking to prevent emergence of severe skin pruritus and rashes[169]. Such processing will, however, alter their immunological antitumor effect due to the decomposition of the thermolabile lentinan by heating.…”

Section: Why the Cancer Cells Survive And How To Reject Them?mentioning

confidence: 99%

Involvement of blood mononuclear cells in the infertility, age-associated diseases and cancer treatment

Bukovský

2016

WJSC

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Blood mononuclear cells consist of T cells and monocyte derived cells. Beside immunity, the blood mononuclear cells belong to the complex tissue control system (TCS), where they exhibit morphostatic function by stimulating proliferation of tissue stem cells followed by cellular differentiation, that is stopped after attaining the proper functional stage, which differs among various tissue types. Therefore, the term immune and morphostatic system (IMS) should be implied. The TCS-mediated morphostasis also consists of vascular pericytes controlled by autonomic innervation, which is regulating the quantity of distinct tissues in vivo. Lack of proper differentiation of tissue cells by TCS causes either tissue underdevelopment, e.g., muscular dystrophy, or degenerative functional failures, e.g., type 1 diabetes and age-associated diseases. With the gradual IMS regression after 35 years of age the gonadal infertility develops, followed by a growing incidence of age-associated diseases and cancers. Without restoring an altered TCS function in a degenerative disease, the implantation of tissue-specific stem cells alone by regenerative medicine can not be successful. Transfused young blood could temporarily restore fertility to enable parenthood. The young blood could also temporarily alleviate aging diseases, and this can be extended by substances inducing IMS regeneration, like the honey bee propolis. The local and/or systemic use of honey bee propolis stopped hair and teeth loss, regressed varicose veins, improved altered hearing, and lowered high blood pressure and sugar levels. Complete regression of stage IV ovarian cancer with liver metastases after a simple elaborated immunotherapy is also reported.

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Section: Why the Cancer Cells Survive And How To Reject Them?mentioning

confidence: 99%

Involvement of blood mononuclear cells in the infertility, age-associated diseases and cancer treatment

Bukovský

2016

WJSC

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“…Since the late 1980s, most shiitake have been cultivated on a sawdust‐based substrate in China 4 , 5 . Shiitake are used in Asian medicine for their antihypertensive, anticarcinogenic and cholesterol‐reducing qualities 1 , 5 . Shiitake spores can cause IgE‐mediated illness, such as hypersensitivity pneumonitis, asthma and allergic rhinitis 1 , 3 , 6 .…”

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confidence: 99%

Shiitake dermatitis: the tale of an under‐recognised, undercooked fungus

McNally

Ross

Wayte

2016

Medical Journal of Australia

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“…1 Histologic features are nonspecific, showing spongiosis, papillary dermis edema and perivascular inflammatory infiltrate, but no vasculitis.…”

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confidence: 99%

“…3,4 Shiitake dermatitis is self-limited and requires only symptomatic treatment with antihistamines and topical or oral corticosteroids. 1 Fully cooking shiitake mushrooms usually prevents recurrence. …”

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confidence: 99%